Difference between revisions of "GcvPB"
| Line 80: | Line 80: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54377 P54377] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P54377 P54377] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU24550] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.4.4.2 1.4.4.2] | * '''E.C. number:''' [http://www.expasy.org/enzyme/1.4.4.2 1.4.4.2] | ||
Revision as of 02:22, 25 June 2009
- Description: glycine decarboxylase (subunit 2)
| Gene name | gcvPB |
| Synonyms | yqhK, gcvP |
| Essential | no |
| Product | glycine decarboxylase (subunit 2) |
| Function | glycine utilization |
| MW, pI | 54 kDa, 5.283 |
| Gene length, protein length | 1464 bp, 488 aa |
| Immediate neighbours | yqhL, gcvPA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU24550
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2 (according to Swiss-Prot)
- Protein family: C-terminal subunit subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: membrane (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P54377
- KEGG entry: [3]
- E.C. number: 1.4.4.2
Additional information
Expression and regulation
- Regulatory mechanism: induction requires a co-operatively acting riboswitch PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Maumita Mandal, Mark Lee, Jeffrey E Barrick, Zasha Weinberg, Gail Mitchell Emilsson, Walter L Ruzzo, Ronald R Breaker
A glycine-dependent riboswitch that uses cooperative binding to control gene expression.
Science: 2004, 306(5694);275-9
[PubMed:15472076]
[WorldCat.org]
[DOI]
(I p)
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
