SigE - Revision history

Jstuelk: /* Original Publications */

2015-04-06T13:29:57Z

‎Original Publications

Jstuelk: /* Extended information on the protein */

2015-04-06T13:29:08Z

‎Extended information on the protein

Julian at 12:55, 24 April 2014

2014-04-24T12:55:24Z

Julian at 11:09, 24 April 2014

2014-04-24T11:09:00Z

Julian at 08:43, 23 April 2014

2014-04-23T08:43:54Z

134.76.38.147 at 13:39, 2 April 2014

2014-04-02T13:39:49Z

134.76.70.252 at 10:43, 7 January 2014

2014-01-07T10:43:53Z

134.76.70.252 at 16:13, 11 November 2013

2013-11-11T16:13:20Z

134.76.70.252 at 13:16, 16 May 2013

2013-05-16T13:16:54Z

134.76.70.252 at 10:09, 14 May 2013

2013-05-14T10:09:58Z

← Older revision		Revision as of 13:29, 6 April 2015
Line 1:		Line 1:
−	* '''Description:~~''' [[RNA polymerase]] sporulation mother cell-specific (early) [[sigma factor]]~~ SigE ~~<br/><br/>~~	+	{{#bank: SigE}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''sigE''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''spoIIGB ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| [[RNA polymerase]] sporulation mother cell-specific <br/>(early) [[sigma factor]] SigE~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| [[transcription]] of sporulation genes (early mother cell)~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15320 sigE]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigE SigE]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=sigE sigE]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 27 kDa, 9.212~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 717 bp, 239 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[spoIIGA]]'', ''[[sigG]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15320 DNA_with_flanks]
−	\|-
−	\|-
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:sigE_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigE_1604771_1605490_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:sigE_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15320]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[transcription]]}},~~
−	~~{{SubtiWiki category\|[[sigma factors and their control]]}},~~
−	~~{{SubtiWiki category\|[[sporulation proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SinR regulon]]}},~~
−	~~{{SubtiWiki regulon\|[[Spo0A regulon]]}},~~
−	~~[[Efp-dependent proteins]]~~
−
−	~~=The [[SigE regulon]]=~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU15320
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15320&redirect=T BSU15320]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIGA-sigE-sigG.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10235]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:''' [[RNA polymerase]] [[sigma factor]], active in the mother cell
−
−	* '''Protein family:''' sigma-70 factor family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[SigE]]-([[RpoB]]-[[RpoC]])
−	** [[SpoIIGA]]-[[SigE]] (Processing) {{PubMed\|21362630}}
−	** [[CsfB]]-[[SigE]] to inhibit [[SigE]] activity {{PubMed\|25835496}}
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15320&redirect=T BSU15320]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P06222 P06222]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15320]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[spoIIGA]]-[[sigE]]-[[sigG]]'' {{PubMed\|1902213}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigE_1604771_1605490_1 sigE] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|2512576}}
−
−	* '''Regulation:'''
−	** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
−
−	* '''Regulatory mechanism:'''
−	** repression by [[SinR]]
−	** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
−
−	* '''Additional information:'''
−	** [[translation]] is likely to require [[Efp]] due to the presence of several consecutive proline residues {{PubMed\|23239624,23239623}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	* [[Bill Haldenwang]], San Antonio, USA
−	* [[Charles Moran]], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed>20833318 </pubmed>~~
−	~~==The [[SigE regulon]]==~~
−	~~<pubmed>12662922,15383836,14523133</pubmed>~~
−	~~==Original Publications==~~
−	~~'''Additional publications:''' {{PubMed\|23169620,21362630,20802044,21478340}}~~
−	<pubmed>7768847,8002606,8449878,10438769,9922240,10869437,13129963,7585939,1729246,9244279,11849534,8231808,8171000,15547282,15882622,9537362,1542693,1946462,8550479,10498732,15978076,9006059,2115864,7473719,12644503,2115871,15028683,7601832,9150232,1624450,1744037,1400231,2495274,11886548,2514119,1744038,14523132,18436644,8288522,15687200,</pubmed>
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 97: / Line 97: @@
 ** [[SigE]]-([[RpoB]]-[[RpoC]])
 ** [[SpoIIGA]]-[[SigE]] (Processing) {{PubMed|21362630}}
 * '''[[Localization]]:'''

@@ Line 46: / Line 46: @@
 {{SubtiWiki category|[[transcription]]}},
 {{SubtiWiki category|[[sigma factors and their control]]}},
-{{SubtiWiki category|[[Sporulation#Sporulation_proteins/_other|sporulation proteins]]}}
+{{SubtiWiki category|[[sporulation proteins]]}}
 = This gene is a member of the following [[regulons]] =

@@ Line 46: / Line 46: @@
 {{SubtiWiki category|[[transcription]]}},
 {{SubtiWiki category|[[sigma factors and their control]]}},
-{{SubtiWiki category|[[sporulation/ other]]}}
+{{SubtiWiki category|[[Sporulation#Sporulation_proteins/_other|sporulation proteins]]}}
 = This gene is a member of the following [[regulons]] =

@@ Line 45: / Line 45: @@
 = [[Categories]] containing this gene/protein =
 {{SubtiWiki category|[[transcription]]}},
-{{SubtiWiki category|[[sigma factors and their control]]}}
+{{SubtiWiki category|[[sigma factors and their control]]}},
 = This gene is a member of the following [[regulons]] =

@@ Line 63: / Line 63: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIGA-sigE-sigG.html]
@@ Line 99: / Line 100: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 18: / Line 18: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigE SigE]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/other_nitrogen_sources/index.html Alternative nitrogen sources]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=sigE sigE]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 9.212

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15320 sigE]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SigE SigE]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigE SigE]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/other_nitrogen_sources/index.html Alternative nitrogen sources]'''

@@ Line 33: / Line 33: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigE_1604771_1605490_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:sigE_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigE_1604771_1605490_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:sigE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15320]]
 |-
 |}

@@ Line 26: / Line 26: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIGA]]'', ''[[sigG]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15320 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15320 DNA_with_flanks]
 |-
 |-