PonA - Revision history

134.76.70.252 at 09:31, 17 April 2014

2014-04-17T09:31:51Z

134.76.70.252 at 11:43, 8 April 2014

2014-04-08T11:43:01Z

134.76.38.147 at 14:02, 2 April 2014

2014-04-02T14:02:23Z

Jstuelk at 09:18, 5 March 2014

2014-03-05T09:18:24Z

Jstuelk at 09:18, 5 March 2014

2014-03-05T09:18:06Z

Jstuelk at 09:16, 5 March 2014

2014-03-05T09:16:18Z

Jstuelk at 09:13, 5 March 2014

2014-03-05T09:13:59Z

134.76.70.252 at 08:42, 12 November 2013

2013-11-12T08:42:08Z

SHalbedel: /* Extended information on the protein */

2013-09-09T14:21:10Z

‎Extended information on the protein

Jstuelk at 12:00, 9 September 2013

2013-09-09T12:00:39Z

← Older revision		Revision as of 09:31, 17 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' class A [[penicillin-binding protein]] 1A/1B, contributes to cell elongation and [[cell division]] <br/><br/>~~	+	{{#bank: PonA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''ponA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' ''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| [[penicillin-binding protein]] 1A/1B~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| bifunctional glucosyltransferase/ transpeptidase~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22320 ponA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=PonA PonA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=PonA PonA]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 99 kDa, 4.752~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 2742 bp, 914 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[recU]]'', ''[[ypoC]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU22320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU22320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU22320 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ponA_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ponA_2341444_2344188_1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:ponA_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22320]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[cell wall synthesis]]}},~~
−	~~{{SubtiWiki category\|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}},~~
−	~~{{SubtiWiki category\|[[membrane proteins]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[SigM regulon]]}}~~
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU22320
−
−	~~===Phenotypes of a mutant ===~~
−	* prevents bulging of the cells when grown at low Mg(2+) concentrations, suppresses the lethal effect of a ''[[mreB]]'' mutation [http://www.ncbi.nlm.nih.gov/sites/entrez/19192185 PubMed]
−	* deletion of ''ponA'' restores growth and normal shape of a ''[[yvcK]]'' mutant on gluconeogenic carbon sources {{PubMed\|21320184}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22320&redirect=T BSU22320]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/recU-ponA.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10954]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−
−	* '''Protein family:'''
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:'''
−
−	* '''Modification:'''
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[EzrA]]-[[PonA]] {{PubMed\|18363795}}
−	** [[GpsB]]-[[PonA]] {{PubMed\|18363795}}
−	** [[MreB]]-[[PonA]] {{PubMed\|19192185}}
−
−	* '''[[Localization]]:'''
−	** membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
−	** localizes to the spore septum during sporulation {{PubMed\|15758244,15262952}}
−	** localizes to the vegetative septum {{PubMed\|15262952}}, this depends on [[YvcK]] {{PubMed\|21320184}}
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU22320&redirect=T BSU22320]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P39793 P39793]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU22320]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''[[recU]]-[[ponA]]'' {{PubMed\|7814321}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ponA_2341444_2344188_1 ponA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:''' [[SigA]] {{PubMed\|22211522}}, [[SigM]] {{PubMed\|18179421}}
−
−	* '''Regulation:''' constitutive during vegetative growth [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 PubMed]
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:''' ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([[BACTH]]), available in [[Jeff Errington]] lab
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~[[Jeff Errington]], Newcastle University, UK [http://www.ncl.ac.uk/camb/staff/profile/jeff.errington homepage]~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−	~~==Reviews==~~
−	~~<pubmed>21371139 </pubmed>~~
−	~~==Original publications==~~
−	~~<pubmed>8606187,15262952,9721295,10322023,19192185,7814321,18363795,14731276, 21320184,18763711 19192185, 18179421 23531131 18363795</pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 17: / Line 17: @@
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=PonA PonA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 99 kDa, 4.752

@@ Line 58: / Line 58: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/recU-ponA.html]
@@ Line 98: / Line 99: @@
 === Database entries ===
 * '''Structure:'''

← Older revision		Revision as of 09:18, 5 March 2014
Line 1:		Line 1:
−	* '''Description:''' class A [[penicillin-binding protein]] 1A/1B, contributes to cell elongation and cell division <br/><br/>	+	* '''Description:''' class A [[penicillin-binding protein]] 1A/1B, contributes to cell elongation and [[cell division]] <br/><br/>

	{\| align="right" border="1" cellpadding="2"		{\| align="right" border="1" cellpadding="2"

← Older revision		Revision as of 09:18, 5 March 2014
Line 1:		Line 1:
−	* '''Description:''' class A [[penicillin-binding protein]] 1A/1B <br/><br/>	+	* '''Description:''' class A [[penicillin-binding protein]] 1A/1B, contributes to cell elongation and cell division <br/><br/>

	{\| align="right" border="1" cellpadding="2"		{\| align="right" border="1" cellpadding="2"

@@ Line 90: / Line 90: @@
 ** [[EzrA]]-[[PonA]] {{PubMed|18363795}}
 ** [[GpsB]]-[[PonA]] {{PubMed|18363795}}
 * '''[[Localization]]:'''

@@ Line 1: / Line 1: @@
-* '''Description:''' [[penicillin-binding protein]] 1A/1B <br/><br/>
+* '''Description:''' class A [[penicillin-binding protein]] 1A/1B <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 64: / Line 64: @@
 === Additional information===
 =The protein=
@@ Line 82: / Line 79: @@
 * '''Kinetic information:'''
-* '''Domains:'''
+* '''[[Domains]]:'''
 * '''Modification:'''
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22320 ponA]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/PonA PonA]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=PonA PonA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 99 kDa, 4.752

@@ Line 15: / Line 15: @@
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU22320 ponA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 99 kDa, 4.752
@@ Line 89: / Line 91: @@
 * '''[[SubtInteract|Interactions]]:'''
 * '''[[Localization]]:'''
@@ Line 145: / Line 148: @@
 <pubmed>21371139 </pubmed>
 ==Original publications==
-<pubmed>8606187,15262952,9721295,10322023,19192185,7814321,18363795,14731276, 21320184,18763711 19192185, 18179421 23531131 </pubmed>
+<pubmed>8606187,15262952,9721295,10322023,19192185,7814321,18363795,14731276, 21320184,18763711 19192185, 18179421 23531131 18363795</pubmed>
 [[Category:Protein-coding genes]]