Btr - Revision history

Jstuelk: /* References */

2014-06-07T16:33:12Z

‎References

Jstuelk at 16:32, 7 June 2014

2014-06-07T16:32:06Z

134.76.38.147 at 12:51, 2 April 2014

2014-04-02T12:51:30Z

134.76.70.252 at 10:02, 7 January 2014

2014-01-07T10:02:32Z

Jstuelk: /* References */

2013-12-28T10:34:32Z

‎References

134.76.70.252 at 12:24, 16 May 2013

2013-05-16T12:24:44Z

134.76.70.252 at 09:19, 14 May 2013

2013-05-14T09:19:01Z

134.76.70.252 at 12:00, 13 May 2013

2013-05-13T12:00:20Z

134.76.70.252 at 09:10, 8 August 2012

2012-08-08T09:10:30Z

134.76.70.252 at 08:11, 8 August 2012

2012-08-08T08:11:26Z

← Older revision		Revision as of 16:33, 7 June 2014
Line 1:		Line 1:
−	* '''Description:''' transcriptional activator ([[transcription factors of the AraC family\|AraC family]]), (AraC family DNA-binding domain fused to [[FeuA]]-like substrate-binding domain), regulation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon <br/><br/>	+	{{#bank: Btr}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''btr''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| ''ybbB, yzbC''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| transcription activator ([[AraC]] family)~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| regulation of iron acquisition~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01640 btr]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Metabolic function and regulation of this protein in [[SubtiPathways\|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=btr btr]'''
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 60 kDa, 6.433~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 1587 bp, 529 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[feuA]]'', ''[[ybbC]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01640 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:ybbB_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbB_183414_185003_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:btr_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01640]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[acquisition of iron]]}},~~
−	~~{{SubtiWiki category\|[[iron metabolism]]}},~~
−	~~{{SubtiWiki category\|[[transcription factors and their control]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−	~~{{SubtiWiki regulon\|[[Fur regulon]]}}~~
−	~~=The [[Btr regulon]]:=~~
−	* ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]''
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU01640
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01640&redirect=T BSU01640]
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ybbB.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10834]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−	** binding of a direct repeat in the ''[[feuA]]'' promoter region and transcription activation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon in the presence of bacillibactin or enterobactin {{PubMed\|17725565,22210890}}
−
−	* '''Protein family:'''[[transcription factors of the AraC family\|AraC family]]
−
−	* '''Paralogous protein(s):'''
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''Domains:'''
−
−	* '''Modification:'''
−
−	* '''Cofactor(s):''' enterobactin, bacillibactin (co-activators) {{PubMed\|17725565}}
−
−	* '''Effectors of protein activity:''' enterobactin, bacillibactin (co-activators) {{PubMed\|17725565}}
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[Btr]]-[[RNA polymerase]] (perhaps [[SigA]]) {{PubMed\|22210890}}
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−	* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU01640&redirect=T BSU01640]
−
−	* '''Structure:'''
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P40408 P40408]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU01640]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''btr'' {{PubMed\|12354229}}
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbB_183414_185003_-1 btr] {{PubMed\|22383849}}
−
−	* '''Sigma factor:'''
−
−	* '''Regulation:'''
−	** expressed under conditions of iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
−
−	* '''Regulatory mechanism:'''
−	** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed]
−
−	* '''Additional information:'''
−	** the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed]
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−
−	~~=References=~~
−
−	~~<pubmed>12884008,17725565, 22210890,12354229, 23199363 23504016 </pubmed>~~
−
−	~~[[Category:Protein-coding genes]]~~

@@ Line 1: / Line 1: @@
-* '''Description:''' transcription activator (AraC family DNA-binding domain fused to [[FeuA]]-like substrate-binding domain), regulation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon <br/><br/>
+* '''Description:''' transcriptional activator ([[transcription factors of the AraC family|AraC family]]), (AraC family DNA-binding domain fused to [[FeuA]]-like substrate-binding domain), regulation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 37: / Line 37: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
-<br/><br/><br/><br/>
+<br/><br/>
 = [[Categories]] containing this gene/protein =
@@ Line 69: / Line 65: @@
 === Additional information===
 =The protein=
@@ Line 80: / Line 73: @@
 ** binding of a direct repeat in the ''[[feuA]]'' promoter region and transcription activation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon in the presence of bacillibactin or enterobactin {{PubMed|17725565,22210890}}
-* '''Protein family:'''
+* '''Protein family:'''[[transcription factors of the AraC family|AraC family]]
 * '''Paralogous protein(s):'''
@@ Line 151: / Line 144: @@
 =References=
-<pubmed>12884008,17725565, 22210890,12354229, 23199363</pubmed>
+<pubmed>12884008,17725565, 22210890,12354229, 23199363 23504016 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 62: / Line 62: @@
 === Database entries ===
 * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ybbB.html]
@@ Line 101: / Line 102: @@
 === Database entries ===
 * '''Structure:'''

@@ Line 16: / Line 16: @@
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01640 btr]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://cellpublisher.gobics.de/view/GqbblRJkBH Metal ion homeostasis]'''
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=btr btr]'''
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 60 kDa, 6.433

@@ Line 149: / Line 149: @@
 =References=
-<pubmed>12884008,17725565, 22210890,12354229, </pubmed>
+<pubmed>12884008,17725565, 22210890,12354229, 23199363</pubmed>
 [[Category:Protein-coding genes]]

@@ Line 29: / Line 29: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbB_183414_185003_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:btr_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybbB_183414_185003_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:btr_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU01640]]
 |-
 |}

@@ Line 24: / Line 24: @@
 |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[feuA]]'', ''[[ybbC]]''
 |-
-|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01640 Advanced_DNA]
+|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01640 DNA_with_flanks]
 |-
 |colspan="2" | '''Genetic context''' <br/> [[Image:ybbB_context.gif]]

@@ Line 13: / Line 13: @@
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of iron acquisition
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://cellpublisher.gobics.de/view/GqbblRJkBH Metal ion homeostasis]'''