BrxA - Revision history

134.76.70.252 at 14:20, 17 April 2014

2014-04-17T14:20:04Z

134.76.70.252 at 11:25, 17 April 2014

2014-04-17T11:25:01Z

Jstuelk at 19:17, 13 December 2013

2013-12-13T19:17:40Z

Jstuelk at 18:58, 13 December 2013

2013-12-13T18:58:13Z

Jstuelk at 18:56, 13 December 2013

2013-12-13T18:56:32Z

Jstuelk: /* Categories containing this gene/protein */

2013-12-13T18:46:20Z

‎Categories containing this gene/protein

Jstuelk at 18:41, 13 December 2013

2013-12-13T18:41:20Z

Jstuelk: Jstuelk moved page YphP to BrxA: 24313874

2013-12-13T18:39:58Z

Jstuelk moved page YphP to BrxA: 24313874

Jstuelk at 19:12, 18 June 2013

2013-06-18T19:12:24Z

134.76.70.252 at 13:42, 16 May 2013

2013-05-16T13:42:14Z

← Older revision		Revision as of 14:20, 17 April 2014
Line 1:		Line 1:
−	* '''Description:~~''' bacilliredoxin <br/><br/>~~	+	{{#bank: BrxA}}

−	~~{\| align="right" border="1" cellpadding="2"~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Gene name'''~~
−	~~\|''brxA''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Synonyms''' \|\| '' yphP''~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Essential''' \|\| no~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Product''' \|\| bacilliredoxin~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Function''' \|\| de-bacillithiolation of S-bacillithiolated [[OhrR]] and [[MetE]]~~
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21860 brxA]
−	\|-
−	\|colspan="2" style="background:#FAF8CC;" align="center"\| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=BrxA BrxA]
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''MW, pI''' \|\| 15 kDa, 4.619~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\| '''Gene length, protein length''' \|\| 432 bp, 144 aa~~
−	\|-
−	~~\|style="background:#ABCDEF;" align="center"\|'''Immediate neighbours''' \|\| ''[[ypiP]]'', ''[[ilvD]]''~~
−	\|-
−	\|style="background:#FAF8CC;" align="center"\|'''Sequences'''\|\|[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU21860 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU21860 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU21860 DNA_with_flanks]
−	\|-
−	~~\|colspan="2" \| '''Genetic context''' <br/> [[Image:yphP_context.gif]]~~
−	~~<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>~~
−	\|-
−	\|colspan="2" \|'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 Expression at a glance]'''   {{PubMed\|22383849}}<br/>[[Image:yphP_expression.png\|500px\|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21860]]
−	\|-
−	\|}
−
−	~~__TOC__~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/><br/><br/>~~
−	~~<br/><br/>~~
−
−	~~= [[Categories]] containing this gene/protein =~~
−	~~{{SubtiWiki category\|[[resistance against oxidative and electrophile stress]]}}~~
−
−	~~= This gene is a member of the following [[regulons]] =~~
−
−
−	~~=The gene=~~
−
−	~~=== Basic information ===~~
−
−	* '''Locus tag:''' BSU21860
−
−	~~===Phenotypes of a mutant ===~~
−
−	~~=== Database entries ===~~
−
−	* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/yphP.html]
−
−	* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11614]
−
−	~~=== Additional information===~~
−
−	~~=The protein=~~
−
−	~~=== Basic information/ Evolution ===~~
−
−	* '''Catalyzed reaction/ biological activity:'''
−	** de-bacillithiolation of S-bacillithiolated [[OhrR]] and [[MetE]] {{PubMed\|24313874}}
−
−	* '''Protein family:''' scpA family (according to Swiss-Prot)
−
−	* '''Paralogous protein(s):''' [[BrxB]]
−
−	~~=== Extended information on the protein ===~~
−
−	* '''Kinetic information:'''
−
−	* '''[[Domains]]:''' contains an CxC redox motif [http://www.ncbi.nlm.nih.gov/pubmed/20308541]
−
−	* '''Modification:'''
−	** S-bacillithiolation upon hypochlorite stress on Cys-53 {{PubMed\|21749987}}
−
−	* '''[[Cofactors]]:'''
−
−	* '''Effectors of protein activity:'''
−
−	* '''[[SubtInteract\|Interactions]]:'''
−	** [[BrxA]]-[[MetE]] {{PubMed\|24313874}}
−	** [[BrxA]]-[[OhrR]] {{PubMed\|24313874}}
−
−	* '''[[Localization]]:'''
−
−	~~=== Database entries ===~~
−
−	* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3FHK 3FHK] {{PubMed\|19653655}}
−
−	* '''UniProt:''' [http://www.uniprot.org/uniprot/P54170 P54170]
−
−	* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21860]
−
−	* '''E.C. number:'''
−
−	~~=== Additional information===~~
−
−	~~=Expression and regulation=~~
−
−	* '''Operon:''' ''brxA'' (according to [http://dbtbs.hgc.jp/COG/prom/yphP.html DBTBS])
−
−	* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 brxA] {{PubMed\|22383849}}
−
−	* '''[[Sigma factor]]:'''
−
−	* '''Regulation:'''
−
−	* '''Regulatory mechanism:'''
−
−	* '''Additional information:'''
−	** number of protein molecules per cell (minimal medium with glucose and ammonium): 730 {{PubMed\|24696501}}
−	** number of protein molecules per cell (complex medium with amino acids, without glucose): 1649 {{PubMed\|24696501}}
−
−	~~=Biological materials =~~
−
−	* '''Mutant:'''
−
−	* '''Expression vector:'''
−
−	* '''lacZ fusion:'''
−
−	* '''GFP fusion:'''
−
−	* '''two-hybrid system:'''
−
−	* '''Antibody:'''
−
−	~~=Labs working on this gene/protein=~~
−
−	~~=Your additional remarks=~~
−	~~[[YpdA]], [[BrxA]], [[BrxB]] and [[YtxJ]] co-occur in those species predicted to synthesize bacillithiol.~~
−
−	~~=References=~~
−	~~<pubmed> 22938038,19653655 20308541 21749987 24313874 </pubmed>~~
−	~~[[Category:Protein-coding genes]]~~

← Older revision		Revision as of 11:25, 17 April 2014
Line 116:		Line 116:

	* '''Additional information:'''		* '''Additional information:'''
		+	** number of protein molecules per cell (minimal medium with glucose and ammonium): 730 {{PubMed\|24696501}}
		+	** number of protein molecules per cell (complex medium with amino acids, without glucose): 1649 {{PubMed\|24696501}}

	=Biological materials =		=Biological materials =

@@ Line 14: / Line 14: @@
 |style="background:#ABCDEF;" align="center"|'''Function''' || de-bacillithiolation of S-bacillithiolated [[OhrR]] and [[MetE]]
 |-
-|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21860 yphP]
+|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21860 brxA]
 |-
 |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 15 kDa, 4.619
@@ Line 64: / Line 66: @@
 * '''Catalyzed reaction/ biological activity:'''
 * '''Protein family:''' scpA family (according to Swiss-Prot)
@@ Line 83: / Line 86: @@
 * '''[[SubtInteract|Interactions]]:'''
 * '''[[Localization]]:'''
@@ Line 102: / Line 107: @@
 * '''Operon:''' ''brxA'' (according to [http://dbtbs.hgc.jp/COG/prom/yphP.html DBTBS])
-* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 yphP] {{PubMed|22383849}}
+* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 brxA] {{PubMed|22383849}}
 * '''[[Sigma factor]]:'''

@@ Line 1: / Line 1: @@
-* '''Description:''' disulfide isomerase, bacilliredoxin <br/><br/>
+* '''Description:''' bacilliredoxin <br/><br/>
 {| align="right" border="1" cellpadding="2"
@@ Line 10: / Line 10: @@
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || disulfide isomerase, bacilliredoxin
+|style="background:#ABCDEF;" align="center"| '''Product''' || bacilliredoxin
 |-
 |style="background:#ABCDEF;" align="center"|'''Function''' || de-bacillithiolation of S-bacillithiolated [[OhrR]] and [[MetE]]

@@ Line 67: / Line 67: @@
 * '''Protein family:''' scpA family (according to Swiss-Prot)
-* '''Paralogous protein(s):''' [[yqiW]]
+* '''Paralogous protein(s):''' [[BrxB]]
 === Extended information on the protein ===
@@ Line 73: / Line 73: @@
 * '''Kinetic information:'''
-* '''Domains:''' contains an CxC redox motif [http://www.ncbi.nlm.nih.gov/pubmed/20308541]
+* '''[[Domains]]:''' contains an CxC redox motif [http://www.ncbi.nlm.nih.gov/pubmed/20308541]
 * '''Modification:'''
 ** S-bacillithiolation upon hypochlorite stress on Cys-53 {{PubMed|21749987}}
-* '''Cofactor(s):'''
+* '''[[Cofactors]]:'''
 * '''Effectors of protein activity:'''
@@ Line 100: / Line 100: @@
 =Expression and regulation=
-* '''Operon:''' ''yphP'' (according to [http://dbtbs.hgc.jp/COG/prom/yphP.html DBTBS])
+* '''Operon:''' ''brxA'' (according to [http://dbtbs.hgc.jp/COG/prom/yphP.html DBTBS])
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 yphP] {{PubMed|22383849}}
@@ Line 129: / Line 129: @@
 =Your additional remarks=
-[[YpdA]], [[YqiW]], [[YphP]] and [[YtxJ]] co-occur in those species predicted to synthesize bacillithiol.
+[[YpdA]], [[BrxA]], [[BrxB]] and [[YtxJ]] co-occur in those species predicted to synthesize bacillithiol.
 =References=
-<pubmed> 22938038,19653655 20308541 21749987</pubmed>
+<pubmed> 22938038,19653655 20308541 21749987 24313874 </pubmed>
 [[Category:Protein-coding genes]]

@@ Line 38: / Line 38: @@
 = [[Categories]] containing this gene/protein =
-{{SubtiWiki category|[[poorly characterized/ putative enzymes]]}}
+{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
 = This gene is a member of the following [[regulons]] =

@@ Line 1: / Line 1: @@
-* '''Description:''' disulfide isomerase, putative bacilliredoxin <br/><br/>
+* '''Description:''' disulfide isomerase, bacilliredoxin <br/><br/>
 {| align="right" border="1" cellpadding="2"
 |-
 |style="background:#ABCDEF;" align="center"|'''Gene name'''
-|''yphP''
+|''brxA''
 |-
-|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
+|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' yphP''
 |-
 |style="background:#ABCDEF;" align="center"| '''Essential''' || no
 |-
-|style="background:#ABCDEF;" align="center"| '''Product''' || disulfide isomerase, putative bacilliredoxin
+|style="background:#ABCDEF;" align="center"| '''Product''' || disulfide isomerase, bacilliredoxin
 |-
-|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+|style="background:#ABCDEF;" align="center"|'''Function''' || de-bacillithiolation of S-bacillithiolated [[OhrR]] and [[MetE]]
 |-
 |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21860 yphP]

← Older revision	Revision as of 18:39, 13 December 2013
(No difference)

@@ Line 35: / Line 35: @@
 <br/><br/><br/><br/>
 <br/><br/><br/><br/>
 <br/><br/>
@@ Line 88: / Line 84: @@
 * '''[[SubtInteract|Interactions]]:'''
-* '''Localization:'''
+* '''[[Localization]]:'''
 === Database entries ===
@@ Line 108: / Line 104: @@
 * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 yphP] {{PubMed|22383849}}
-* '''Sigma factor:'''
+* '''[[Sigma factor]]:'''
 * '''Regulation:'''

@@ Line 27: / Line 27: @@
   <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 |-
-|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yphP_expression.png|500px]]
+|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yphP_2300221_2300655_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:yphP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21860]]
 |-
 |}