SubtiWiki - User contributions [en]

YwcI

2014-04-24T13:02:51Z

Julian:

* '''Description:''' unknown 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ywcI''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ipa-46d ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38080 ywcI]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 11 kDa, 11.112
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 300 bp, 100 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sacT]]'', ''[[vpr]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU38080 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU38080 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU38080 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:ywcI_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywcI_3907012_3907314_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ywcI_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU38080]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[proteins of unknown function]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU38080

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU38080&redirect=T BSU38080]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10592]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU38080&redirect=T BSU38080]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P39607 P39607]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU38080]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[ywcI]]'' {{PubMed|21815947}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywcI_3907012_3907314_-1 ywcI] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]

* '''Regulatory mechanism:'''

* '''Additional information:'''
** the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] {{PubMed|21815947}}

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=
<pubmed>12107147, 21815947</pubmed>

[[Category:Protein-coding genes]]

YwbA

2014-04-24T13:02:41Z

Julian:

YvnB

2014-04-24T13:02:33Z

Julian:

YugT

2014-04-24T13:02:26Z

Julian:

YugS

2014-04-24T13:02:16Z

Julian:

YthB

2014-04-24T13:02:09Z

Julian:

YthA

2014-04-24T13:02:00Z

Julian:

YtaG

2014-04-24T13:01:52Z

Julian:

YrzI

2014-04-24T13:01:38Z

Julian:

YrzF

2014-04-24T13:01:19Z

Julian:

* '''Description:''' unknown 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yrzF''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27785 yrzF]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 9.185
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 645 bp, 215 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrbE]]'', ''[[yrzH]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27785 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27785 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27785 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:yrzF_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrzF_2840110_2840757_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yrzF_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27785]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[proteins of unknown function]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU27785

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27785&redirect=T BSU27785]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13816]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''Interactions:'''

* '''Localization:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27785&redirect=T BSU27785]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O32057 O32057]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27780]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrzF_2840110_2840757_1 yrzF] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

YrbD

2014-04-24T13:01:10Z

Julian:

* '''Description:''' sodium/proton-dependent alanine transporter 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yrbD''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || sodium/proton-dependent alanine transporter
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || uptake of alanine
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27810 yrbD]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=yrbD yrbD]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 51 kDa, 9.383
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1452 bp, 484 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrzT]]'', ''[[yrbC]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27810 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:yrbD_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrbD_2841611_2843065_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yrbD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27810]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[biosynthesis/ acquisition of amino acids]]}},
{{SubtiWiki category|[[utilization of amino acids]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU27810

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27810&redirect=T BSU27810]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13784]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''[[Domains]]:'''

* '''Modification:'''

* '''[[Cofactors]]:'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU27810&redirect=T BSU27810]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O32060 O32060]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU27810]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yrbD_2841611_2843065_1 yrbD] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

YqaO

2014-04-24T13:01:03Z

Julian:

YqaN

2014-04-24T13:00:52Z

Julian:

YpuI

2014-04-24T13:00:43Z

Julian:

YpqP

2014-04-24T13:00:35Z

Julian:

* '''Description:''' similar to capsular polysaccharide biosynthesis, in ''B. subtilis'' 168 the gene is disrupted by the [[SP-beta prophage]] 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ypqP''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21670 ypqP]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || - , -
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 606 bp, -
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yokA]]'', ''[[msrB]]''
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ypqP_nucleotide.txt Gene sequence (+200bp) ]'''
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ypqP_protein.txt Protein sequence]'''
|-
|colspan="2" | '''Genetic context''' [[Image:ypqP_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypqP_2286448_2287053_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ypqP_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21670]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[capsule biosynthesis and degradation]]}},
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU21670

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU21670&redirect=T BSU21670]

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ypqP.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11629]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU21670&redirect=T BSU21670]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P54183 P54183]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU21670]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''ypqP'' (accoriding to [http://dbtbs.hgc.jp/COG/prom/ypqP.html DBTBS])

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypqP_2286448_2287053_1 ypqP] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

YozP

2014-04-24T13:00:27Z

Julian:

SprB

2014-04-24T13:00:18Z

Julian:

* '''Description:''' unknown 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yotN''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19820 yotN]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6 kDa, 5.163
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 174 bp, 58 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yodU]]'', ''[[yotM]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19820 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19820 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19820 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:yotN_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yotN_2152086_2152262_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yotN_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19820]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[SP-beta prophage]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU19820

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19820&redirect=T BSU19820]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13747]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19820&redirect=T BSU19820]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34850 O34850]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU19820]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yotN_2152086_2152262_-1 yotN] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

YoqH

2014-04-24T13:00:10Z

Julian:

YosA

2014-04-24T12:59:54Z

Julian:

YodU

2014-04-24T12:59:46Z

Julian:

* '''Description:''' similar to capsular polysaccharide biosynthesis 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yodU''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ypqP''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19810 yodU]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 15 kDa, 9.819
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 423 bp, 141 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[phy]]'', ''[[yotN]]''
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yodU_nucleotide.txt Gene sequence (+200bp) ]'''
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/yodU_protein.txt Protein sequence]'''
|-
|colspan="2" | '''Genetic context''' [[Image:yodU_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypqP_2151626_2152045_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yodU_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19810]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[capsule biosynthesis and degradation]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU19810

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19810&redirect=T BSU19810]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG13547]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''
** secreted (according to Swiss-Prot)

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU19810&redirect=T BSU19810]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/O34490 O34490]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU19810]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypqP_2151626_2152045_1 yodU] {{PubMed|22383849}}

* '''[[Sigma factor]]:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

YocN

2014-04-24T12:59:37Z

Julian:

YoaU

2014-04-24T12:59:26Z

Julian:

YmfD

2014-04-24T12:59:18Z

Julian:

YloB

2014-04-24T12:59:07Z

Julian:

YjzK

2014-04-24T12:58:58Z

Julian:

YjzC

2014-04-24T12:58:50Z

Julian:

YjaU

2014-04-24T12:58:41Z

Julian:

YizD

2014-04-24T12:58:15Z

Julian:

* '''Description:''' unknown 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yizD''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || -
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11549 yizD]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 6.4 kDa, 9.696
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 165 bp, 55 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[pepF]]'', ''[[yjbH]]''
|-
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt Gene sequence (+200bp) ]'''
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]'''
|-
|colspan="2" | '''Genetic context''' [[Image:yizD_context.gif]]
|-
|colspan="2" |'''[None Expression at a glance]'''   {{PubMed|22383849}} [[Image:yizD_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU11549]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[proteins of unknown function]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU11549

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11549&redirect=T BSU11549]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' no entry

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU11549&redirect=T BSU11549]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/C0H3Y6 C0H3Y6]

* '''KEGG entry:'''

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''
** A [[ncRNA]] is predicted between ''[[yizD]]'' and ''[[yjbH]]'' {{PubMed|20525796}}

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=
<pubmed>20525796</pubmed>
[[Category:Protein-coding genes]]

YizC

2014-04-24T12:58:04Z

Julian:

YhzF

2014-04-24T12:57:51Z

Julian:

YhzD

2014-04-24T12:57:42Z

Julian:

YheA

2014-04-24T12:57:32Z

Julian:

YgzC

2014-04-24T12:57:23Z

Julian:

YgzA

2014-04-24T12:57:14Z

Julian:

YezF

2014-04-24T12:57:06Z

Julian:

YdzR

2014-04-24T12:56:57Z

Julian:

YdzH

2014-04-24T12:56:25Z

Julian:

YczM

2014-04-24T12:56:17Z

Julian:

YclG

2014-04-24T12:56:05Z

Julian:

* '''Description:''' unknown 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yclG''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03680 yclG]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 62 kDa, 5.217
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1752 bp, 584 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yclF]]'', ''[[gerKD]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03680 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03680 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03680 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:yclG_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yclG_417993_419747_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yclG_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03680]]
|-
|}

__TOC__
 
 
 
 
 

 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[proteins of unknown function]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU03680

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03680&redirect=T BSU03680]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12028]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:'''

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03680&redirect=T BSU03680]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P94409 P94409]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03680]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yclG_417993_419747_1 yclG] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''

* '''Regulatory mechanism:'''

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

[[Category:Protein-coding genes]]

DtpT

2014-04-24T12:55:55Z

Julian:

* '''Description:''' peptide transporter 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yclF''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' dtpT''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || peptide transporter
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || uptake of di- and tripeptides
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03670 yclF]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 53 kDa, 9.92
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1476 bp, 492 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yclE]]'', ''[[yclG]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03670 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:yclF_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dtpT_416235_417713_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:yclF_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03670]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transporters/ other]]}},
{{SubtiWiki category|[[utilization of nitrogen sources other than amino acids]]}},
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[ScoC regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU03670

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03670&redirect=T BSU03670]

* '''DBTBS entry:''' no entry

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12027]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:'''

* '''Protein family:''' POT family of secondary (PMF-dependent) transporters

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU03670&redirect=T BSU03670]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P94408 P94408]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU03670]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:'''

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dtpT_416235_417713_-1 yclF] {{PubMed|22383849}}

* '''Sigma factor:'''

* '''Regulation:'''
** repressed during exponential growth ([[ScoC]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/11717292 PubMed]

* '''Regulatory mechanism:'''
** [[ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/11717292 PubMed]

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed>11717292, 8458848 </pubmed>

[[Category:Protein-coding genes]]

Ugd

2014-04-24T12:55:46Z

Julian:

* '''Description:''' UDP-glucose dehydrogenase 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''ugd''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ywqF''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || UDP-glucose dehydrogenase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36230 ugd]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=Ugd Ugd]
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 5.03
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1320 bp, 440 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywqG]]'', ''[[ptpZ]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36230 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36230 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36230 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:ywqF_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywqF_3729488_3730810_-1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:ugd_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36230]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[phosphoproteins]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU36230

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU36230&redirect=T BSU36230]

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ywqF.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12510]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH (according to Swiss-Prot)

* '''Protein family:''' UDP-glucose/GDP-mannose dehydrogenase family (according to Swiss-Prot)

* '''Paralogous protein(s):''' [[TuaD]], [[YtcA]]

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''[[Domains]]:'''

* '''Modification:''' phosphorylation on Tyr-70 by [[PtkA]] {{PubMed|12970183}}, dephosphorylated by [[PtpZ]] {{PubMed|15866923}}

* '''[[Cofactors]]:'''

* '''Effectors of protein activity:''' phosphorylation by [[PtkA]] stimulates activity of Ugd {{PubMed|15741737}}

* '''[[SubtInteract|Interactions]]:'''

* '''[[Localization]]:''' cytoplasm (according to Swiss-Prot)

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU36230&redirect=T BSU36230]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P96718 P96718]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU36230]

* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.22 1.1.1.22]

=== Additional information===

=Expression and regulation=
* '''Operon:''' ''[[tkmA]]-[[ptkA]]-[[ptpZ]]-[[ugd]]'' {{PubMed|20815827,12970183}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ywqF_3729488_3730810_-1 ugd] {{PubMed|22383849}}

* '''Sigma factor:''' [[SigA]] {{PubMed|20815827}}

* '''Regulation:'''

* '''Regulatory mechanism:'''
** [[DegU]]-P: transcription repression {{PubMed|20815827}}

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

=Your additional remarks=

=References=

<pubmed> 12970183, 19258708 15741737 15866923 20815827 24728941 </pubmed>

[[Category:Protein-coding genes]]

SpoIIE

2014-04-24T12:55:37Z

Julian:

* '''Description:''' [[Protein kinases and phosphatases|protein serine phosphatase]], septum-associated PP2C, dephosphorylation of [[SpoIIAA]] 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''spoIIE''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''spoIIH, spoIIK ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || [[Protein kinases and phosphatases|protein serine phosphatase]], septum-associated PP2C
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigF]] activity required for normal formation of the asymmetric septum
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00640 spoIIE]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SpoIIE SpoIIE]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=spoIIE spoIIE]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 91 kDa, 6.137
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 2481 bp, 827 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[trnSL-Glu1]]'', ''[[yabS]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00640 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00640 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00640 DNA_with_flanks]
|-
|colspan="2" | '''Genetic context''' [[Image:spoIIE_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIIE_70538_73021_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:spoIIE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00640]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[protein modification]]}},
{{SubtiWiki category|[[sigma factors and their control]]}},
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[Spo0A regulon]]}}

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU00640

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00640&redirect=T BSU00640]

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIE.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10127]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' dephosphorylation of [[SpoIIAA]]

* '''Protein family:''' PP2C [[Protein kinases and phosphatases|phosphatase]]

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''
** [[SpoIIE]]-[[FtsZ]]
** [[SpoIIE]]-[[SpoIIAB]]
** [[SpoIIE]]-[[SpoIIE]]
** [[SpoIIQ]]-[[SpoIIE]]
** forms a dimer {{PubMed|22115775}}

* '''[[Localization]]:'''
** cell membrane (according to Swiss-Prot)
** localizes to the polar cell division sites where it causes [[FtsZ]] to relocate from mid-cell to form polar Z-rings
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU00640&redirect=T BSU00640]

* '''Structure:'''
** [http://www.rcsb.org/pdb/explore.do?structureId=3T91 3T91] (phosphatase domain) {{PubMed|22115775}}
* '''UniProt:''' [http://www.uniprot.org/uniprot/P37475 P37475]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00640]

* '''E.C. number:''' [http://www.expasy.org/enzyme/3.1.3.16 3.1.3.16]

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''spoIIE'' (DBTBS)

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoIIE_70538_73021_1 spoIIE] {{PubMed|22383849}}

* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084 PubMed]

* '''Regulation:'''
** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084,15687200 PubMed]

* '''Regulatory mechanism:'''
** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084,15687200 PubMed]

* '''Additional information:'''

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

[[Imrich Barak]], Slovak Academy of Science, Bratislava, Slovakia [http://imb.savba.sk/~barak/ homepage]

=Your additional remarks=

=References=
==Modeling of [[SigF]] activation==
<pubmed> 24067622 22312331</pubmed>

==Original Publications==
<pubmed>7570023,7570022,12180929,9077448,9364910,10323866,8622920,12007411,16824103,10476035,10747015,10322028,15978076,9495766,14744853,9642177,15866939,8846916,1556084,1948031,9573053,18077456,11846550,9150232,15205443,1556084,15687200, 19578359 10049355 20817757 22115775</pubmed>

[[Category:Protein-coding genes]]

SigE

2014-04-24T12:55:24Z

Julian:

* '''Description:''' [[RNA polymerase]] sporulation mother cell-specific (early) [[sigma factor]] SigE 

{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''sigE''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''spoIIGB ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || [[RNA polymerase]] sporulation mother cell-specific (early) [[sigma factor]] SigE
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || [[transcription]] of sporulation genes (early mother cell)
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15320 sigE]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=SigE SigE]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: [http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=sigE sigE]'''
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 9.212
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 717 bp, 239 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIGA]]'', ''[[sigG]]''
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15320 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15320 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15320 DNA_with_flanks]
|-
|-
|-
|colspan="2" | '''Genetic context''' [[Image:sigE_context.gif]]
<div align="right"> This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigE_1604771_1605490_1 Expression at a glance]'''   {{PubMed|22383849}} [[Image:sigE_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15320]]
|-
|}

__TOC__
 
 
 
 

= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[transcription]]}},
{{SubtiWiki category|[[sigma factors and their control]]}},
{{SubtiWiki category|[[sporulation proteins]]}}

= This gene is a member of the following [[regulons]] =
{{SubtiWiki regulon|[[SinR regulon]]}},
{{SubtiWiki regulon|[[Spo0A regulon]]}},
[[Efp-dependent proteins]]

=The [[SigE regulon]]=

=The gene=

=== Basic information ===

* '''Locus tag:''' BSU15320

===Phenotypes of a mutant ===

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15320&redirect=T BSU15320]

* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/spoIIGA-sigE-sigG.html]

* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10235]

=== Additional information===

=The protein=

=== Basic information/ Evolution ===

* '''Catalyzed reaction/ biological activity:''' [[RNA polymerase]] [[sigma factor]], active in the mother cell

* '''Protein family:''' sigma-70 factor family (according to Swiss-Prot)

* '''Paralogous protein(s):'''

=== Extended information on the protein ===

* '''Kinetic information:'''

* '''Domains:'''

* '''Modification:'''

* '''Cofactor(s):'''

* '''Effectors of protein activity:'''

* '''[[SubtInteract|Interactions]]:'''
** [[SigE]]-([[RpoB]]-[[RpoC]])
** [[SpoIIGA]]-[[SigE]] (Processing) {{PubMed|21362630}}

* '''[[Localization]]:'''

=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU15320&redirect=T BSU15320]

* '''Structure:'''

* '''UniProt:''' [http://www.uniprot.org/uniprot/P06222 P06222]

* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15320]

* '''E.C. number:'''

=== Additional information===

=Expression and regulation=

* '''Operon:''' ''[[spoIIGA]]-[[sigE]]-[[sigG]]'' {{PubMed|1902213}}

* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigE_1604771_1605490_1 sigE] {{PubMed|22383849}}

* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2512576}}

* '''Regulation:'''
** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]

* '''Regulatory mechanism:'''
** repression by [[SinR]]
** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]

* '''Additional information:'''
** [[translation]] is likely to require [[Efp]] due to the presence of several consecutive proline residues {{PubMed|23239624,23239623}}

=Biological materials =

* '''Mutant:'''

* '''Expression vector:'''

* '''lacZ fusion:'''

* '''GFP fusion:'''

* '''two-hybrid system:'''

* '''Antibody:'''

=Labs working on this gene/protein=

* [[Bill Haldenwang]], San Antonio, USA
* [[Charles Moran]], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]

=Your additional remarks=

=References=
==Reviews==
<pubmed>20833318 </pubmed>
==The [[SigE regulon]]==
<pubmed>12662922,15383836,14523133</pubmed>
==Original Publications==
'''Additional publications:''' {{PubMed|23169620,21362630,20802044,21478340}}
<pubmed>7768847,8002606,8449878,10438769,9922240,10869437,13129963,7585939,1729246,9244279,11849534,8231808,8171000,15547282,15882622,9537362,1542693,1946462,8550479,10498732,15978076,9006059,2115864,7473719,12644503,2115871,15028683,7601832,9150232,1624450,1744037,1400231,2495274,11886548,2514119,1744038,14523132,18436644,8288522,15687200,</pubmed>

[[Category:Protein-coding genes]]

Tdh

2014-04-24T12:55:08Z

Julian:

RacA

2014-04-24T12:55:01Z

Julian:

PucH

2014-04-24T12:54:41Z

Julian:

NagZ

2014-04-24T12:54:32Z

Julian:

NrnB

2014-04-24T12:54:19Z

Julian:

MurR

2014-04-24T12:54:08Z

Julian:

MurQ

2014-04-24T12:53:59Z

Julian: