rplL
168
ribosomal protein bL12
locus
BSU_01050
Molecular weight
12.61 kDa
pI
4.36
function
translation
product
ribosomal protein L12 (bL12)
essential
yes
synonyms
rplL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0222 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
120,607 120,978
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]
The protein
Protein family
Bacterial [wiki|ribosomal protein] bL12 family (single member, according to UniProt)
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|P02394]
[wiki|Localization]
[wiki|ribosome] (according to UniProt)
Additional information
belongs to the 100 most abundant proteins [PubMed|15378759]
Expression and Regulation
Operons
genes
[gene|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ]-[gene|E72910604D3DC2A62AE8A951F55570EA2838B250|rplL]
description
[Pubmed|26101249]
regulation
termination/ antitermination ([protein|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|L10]-[protein|E72910604D3DC2A62AE8A951F55570EA2838B250|L12]4 complex) [Pubmed|26101249]
regulatory mechanism
[protein|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ]: termination, at excess of the [protein|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ]-[protein|E72910604D3DC2A62AE8A951F55570EA2838B250|rplL]4 complex, in [regulon|protein:5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ regulon]
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
[protein|E72910604D3DC2A62AE8A951F55570EA2838B250|rplL]: termination, at excess of the [protein|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ]-[protein|E72910604D3DC2A62AE8A951F55570EA2838B250|rplL]4 complex, in [regulon|protein:E72910604D3DC2A62AE8A951F55570EA2838B250|rplL regulon]
genes
[gene|F94A1C14912F35ADB4C611AA17D55268CC26160D|rplK]-[gene|44D4CE353E1E532664A508CBE8B49AC8BB861B53|rplA]-[gene|E4D89640D0F0A31A2814D20FB5425FDB0B46A43D|BSU_misc_RNA_3]-[gene|5EF3A7953AA97D2B44C967542A53FEA7F36D7BA3|rplJ]-[gene|E72910604D3DC2A62AE8A951F55570EA2838B250|rplL]
description
[pubmed|22383849]
regulation
[protein|CEE73284EFC0DBE8870CE0B474922DED79475A57|rel] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
regulatory mechanism
stringent response: negative regulation, [pubmed|11948165], in [regulon|other_regulator:stringent response|stringent response]
References
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Time of last update: 2024-12-19 10:45:28
Author of last update: Jstuelk