Tue Dec 13 2016 11:16:37 GMT+0100 (CET)2025-05-22 16:51:54
locus
BSU38770
BSU_38770
ec
outlinks
bsu
BSU38770
BSU_38770
aminos
MGELQTHMQLQTDTIHEGVRKENWFAKAMNIKVGIIPLPVYALLFILITVFVMHHDVKSDILTSIAVMAFFGFTFAQIGKSIPIVRSIGGPAILATFIPSAVVYYHLLPNDIVKSTTEFTENSNFLYLFIAGIVVGSILGMKRETLVKAFMKIFIPLIVGSVTAAIVGLAVGTLLGLGFQHTLLYIVIPIMAGGVGEGAIPLSIGYSDIMPISQGEAFALVLPSIMLGSLCAIILAGLLNRIGKKKPEWTGNGKVDRSEEESPALEESQSGQQMFNLSLFASGGILAVSLYLVGMLAHDFFGFPAPVAMLLLAVLIKLFRLVPASIENGAFGVSRFFSTAVTYPLLFAIGVSMTPWDKLVAAFNLSNIITILSVVVTMMAVGFFTGKWLNMYPIETAIINACHSGQGGTGDVAILSAAERLELMPFAQVSTRIGGAITVSLTLLLLHQFY
[SW|Categories] containing this gene/protein
[SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
3,979,753 -> 3,981,105
The protein
Protein family
sodium:citrate (SCF) symporter family (according to Swiss-Prot) 2-hydroxycarboxylate transporter family
sodium:citrate (SCF) symporter family (together with [[protein|MaeN]], according to UniProt)
The protein
Paralogous protein(s)
[[protein|MaeN]]
[[this]]
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cell membrane (according to UniProt)
Expression and Regulation
Operon
''[[protein|cimH]]'' [Pubmed|21815947]
Expression and Regulation
Regulation
repressed by glucose ([[protein|CcpA]]) [Pubmed|10666464]
Expression and Regulation
Regulatory mechanism
[[protein|CcpA]]: transcription repression [Pubmed|10666464]
Expression and Regulation
Additional information
the mRNA is substantially stabilized upon depletion of [[Rny|RNase Y]] [PubMed|21815947]
References
Original publications
proteinLength
450
geneLength
1353
Gene
Coordinates
3,979,753 → 3,981,105
The protein
Structure
[PDB|5X9R] (from Klebsiella pneumoniae, 34% identity) [pubmed|28566738]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B744 (yxkJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1743 NBRP B. subtilis, Japan]
BKE38770 (Δ[[gene|cimH]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGAAAAACCTCCCCTAT, downstream forward: _UP4_TGATCCCCGCAAGCAAGTTC
BKK38770 (Δ[[gene|cimH]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38770 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGAAAAACCTCCCCTAT, downstream forward: _UP4_TGATCCCCGCAAGCAAGTTC