Tue Dec 13 2016 11:16:32 GMT+0100 (CET)2025-05-10 08:24:29
description
ABC transporter (ATP-binding protein, exporter) for the export of the SdpC toxin
[SW|ABC transporter ](ATP-binding protein, exporter) for the export of the [[protein|SdpC]] toxin
locus
BSU14360
BSU_14360
function
resistance to SdpC toxin
resistance to [[protein|SdpC]] toxin
product
ABC transporter (ATP-binding protein, exporter)
[SW|ABC transporter ](ATP-binding protein, exporter)
ec
outlinks
bsu
BSU14360
BSU_14360
aminos
MIQLSNVRKSYQIGKETFDVLHSIDLDIHQGEYVSIMGPSGSGKSTIMNIIGCLDRPTSGTYQLDGEDISSYKDKELAAVRNRSIGFVFQQFQLLPRLNAKKNVELPMIYSGIGKKERQERAERALEKVGLADRMLHMPNELSGGQKQRVAIARAIVNEPKLILADEPTGALDTKTSEAIMDQFTALNAEGTTIVLVTHEPEVADCTNRIVMVRDGNIVPASSGQRSVGE
[SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,505,416 -> 1,506,108
The protein
[SW|Interactions]
[[protein|YknY]]-[[protein|YknZ]] [Pubmed|10092453]
[[protein|YknW]]-([[protein|YknX]]-([[protein|YknY]]-[[protein|YknZ]]) [Pubmed|22707703]
Expression and Regulation
Operon
''[[protein|yknW]]-[[protein|yknX]]-[[protein|yknY]]-[[protein|yknZ]]'' [Pubmed|9987136]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigW]] [Pubmed|9987136]
Expression and Regulation
Regulation
repressed during logrithmic growth ([[protein|AbrB]]) [Pubmed|12076816]
Expression and Regulation
Regulatory mechanism
[[protein|AbrB]]: transcription repression [Pubmed|12076816]
References
proteinLength
230
geneLength
693
Gene
Coordinates
1,505,416 → 1,506,108
The protein
Protein family
[SW|ABC transporter superfamily] (according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|ABC transporter domain] (aa 2-230) (according to UniProt)
The protein
Structure
[PDB|1L2T] (from Methanocaldococcus jannaschii, 52% identity) [pubmed|12150914]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B350 (yknY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1349 NBRP B. subtilis, Japan]
BKE14360 (Δ[[gene|yknY]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCGCACATTAGAAAGCTGAA, downstream forward: _UP4_TCCGGACAAAGGAGTGTGGG
BKK14360 (Δ[[gene|yknY]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCGCACATTAGAAAGCTGAA, downstream forward: _UP4_TCCGGACAAAGGAGTGTGGG