Tue Dec 13 2016 11:16:32 GMT+0100 (CET)2025-05-13 03:10:02
description
ABC-type antimicrobial peptide transporter (permease) for the export of the SdpC toxin
ABC-type antimicrobial peptide transporter (permease) for the export of the [[protein|SdpC]] toxin
locus
BSU14350
BSU_14350
function
resistence against SdpC toxin
resistence against [[protein|SdpC]] toxin
ec
outlinks
bsu
BSU14350
BSU_14350
aminos
MKKVWIGIGIAVIVALFVGINIYRSAAPTSGSAGKEVQTGSVEENEISSTVMVPGTLKFSNEQYVFYEADKGTLEDIKVKEGDKVKKGTALVTYTNEQLSLEKEQNQLTSESNRLQIDQIQEKLKALDSKERELEKQVGKKEAEKQIESERTELQMQKKTAEIELKQTELQRQSLANRVSDLEVKSEIEGTVISVNQEAASKKSDIQEPVIHIGNPKDLVVSGKLSEYDTLKVKKGQKVTLTSDVIQGKTWKGTVSAVGLVPDQQESAAAQGTEQAVQYPLQVKIKGNLPEGKPGFKFIMNIETDKRKANTLPSKAVKKEDDQYYVYTVKDGKAKRVDVKIGEVTDDLTEIKEGLTQDDQVILNPSDQVTDGMEVKS
[SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,504,282 -> 1,505,415
The protein
[SW|Interactions]
[[protein|YknW]]-([[protein|YknX]]-([[protein|YknY]]-[[protein|YknZ]]) [Pubmed|22707703]
Expression and Regulation
Operon
''[[protein|yknW]]-[[protein|yknX]]-[[protein|yknY]]-[[protein|yknZ]]'' [Pubmed|9987136]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigW]] [Pubmed|9987136]
Expression and Regulation
Regulation
repressed during logrithmic growth ([[protein|AbrB]]) [Pubmed|12076816]
Expression and Regulation
Regulatory mechanism
[[protein|AbrB]]: transcription repression [Pubmed|12076816]
References
proteinLength
377
geneLength
1134
Gene
Coordinates
1,504,282 → 1,505,415
The protein
Protein family
[SW|Membrane fusion protein (MFP) (TC 8.A.1) family] (according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|4DK0] (from Actinobacillus actinomycetemcomitans, 24% identity) [pubmed|22308040]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B349 (yknX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1348 NBRP B. subtilis, Japan]
BKE14350 (Δ[[gene|yknX]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCCGATCCAGACTTTTTTCA, downstream forward: _UP4_GACGGAATGGAAGTGAAATC
BKK14350 (Δ[[gene|yknX]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14350 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TCCGATCCAGACTTTTTTCA, downstream forward: _UP4_GACGGAATGGAAGTGAAATC