Sun Dec 18 2016 20:11:32 GMT+0100 (CET)2025-05-22 15:52:05
title
ykzW
sr1
description
small regulatory RNA controlling AhrC expression, regulatory peptide
small regulatory RNA controlling [[protein|AhrC ]]expression, regulatory peptide
locus
BSU14629
BSU_14629
ec
outlinks
bsupath
ykzW_1534120_1534239_1
outlinks
uniprot
C0H410
[http://www.uniprot.org/uniprot/C0H410 C0H410]
outlinks
bsu
BSU14629
[SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of amino acids], [SW|utilization of amino acids], [SW|ncRNA]
Gene
Coordinates on the chromosome (coding sequence)
1,534,120 -> 1,534,239
The peptide
Catalyzed reaction/ biological activity:
the peptide controls the stability of the ''[[protein|cggR]]-[[protein|gapA]]'' mRNA [Pubmed|20444087]
the peptide controls the stability of the ''[[gene|cggR]]-[[gene|gapA]]'' mRNA [Pubmed|20444087]
The peptide
Protein family:
the peptide is conserved in bacilli
The peptide
[SW|Interactions]:
[[protein|GapA]]-[[protein|YkzW]] [Pubmed|20444087]
The RNA
Catalyzed reaction/ biological activity
hybridizes to ''[[protein|ahrC]]'' mRNA and inhibits [[protein|AhrC]] translation [Pubmed|17020585]
The RNA
[SW|Interactions]
[[protein|ahrC]] mRNA-[[protein|ykzW]] RNA [Pubmed|20444087]
The RNA
Additional information
Information on the structure of the RNA can be found in [Pubmed|17020585]
Database entries
BsubCyc
[http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU14629&redirect=T BSU14629]
Database entries
UniProt
[http://www.uniprot.org/uniprot/C0H410 C0H410]
Expression and Regulation
Operon
sr1 [Pubmed|16164558]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|16164558]
Expression and Regulation
Regulation
Repressed in the presence of glucose by [[protein|CcpN]] [Pubmed|16164558]
Expression and Regulation
Regulatory mechanism
transcription repression [Pubmed|16164558]
Biological materials
Mutant
168 ykzW::cat, available in [SW|Sabine Brantl]'s lab
GP2210 (''[[protein|ykzW]]''::''cat''), available in [SW|Jörg Stülke]'s lab
GP2215 (''[[protein|ykzW]]''::''aphA3''), available in [SW|Jörg Stülke]'s lab
GP2216 (''[[protein|ykzW]]''::''phleo''), available in [SW|Jörg Stülke]'s lab
168 ykzW::cat, available in [SW|Sabine Brantl]'s lab
GP2210 (''[[gene|sr1]]''::''cat''), available in [SW|Jörg Stülke]'s lab
GP2215 (''[[gene|sr1]]''::''aphA3''), available in [SW|Jörg Stülke]'s lab
GP2216 (''[[gene|sr1]]''::''phleo''), available in [SW|Jörg Stülke]'s lab
BKE14629 (Δ[[gene|sr1]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14629 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTTATTCCCCATTTC, downstream forward: _UP4_TAAAAAAAAGCATGCGGCTT
BKK14629 (Δ[[gene|sr1]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14629 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTTATTCCCCATTTC, downstream forward: _UP4_TAAAAAAAAGCATGCGGCTT
Labs working on this gene/protein
[SW|Sabine Brantl], Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany [http://www.uni-jena.de/AG_Bakteriengenetik_(_Doz__Dr__Sabine_Brantl_).html homepage]
References
outlinks
BsubCyc
[http://bsubcyc.org/BSU_B/NEW-IMAGE?type=NIL&object=BSU_14629&redirect=T BSU_14629]
Gene
Coordinates
1,534,120 → 1,534,239
RNA
Catalyzed reaction/ biological activity
hybridizes to ''[[gene|ahrC]]'' mRNA and inhibits [[protein|AhrC]] translation [Pubmed|17020585]
RNA
[SW|Interactions]
[[gene|ahrC]] mRNA-[[gene|sr1]] RNA [Pubmed|20444087]
[[protein|CsrA]]-[[gene|sr1]] RNA to promote base pairing between the [[gene|sr1]] RNA and the [[gene|ahrC]] mRNA and to control arginine metabolism [pubmed|31043113]
RNA
Additional information
Information on the structure of RNA can be found in [Pubmed|17020585]
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
labs
[SW|Sabine Brantl], Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany [http://www.uni-jena.de/AG_Bakteriengenetik_(_Doz__Dr__Sabine_Brantl_).html homepage]
References
Reviews
References
Original Publications
The peptide
Protein family
the peptide is conserved in bacilli
The peptide
[SW|Interactions]
[[protein|GapA]]-[[protein|Sr1]] [Pubmed|20444087]