Mon Aug 31 2015 13:53:27 GMT+0200 (CEST)2025-05-14 20:54:37
locus
BSU10170
BSU_10170
outlinks
bsu
BSU10170
BSU_10170
syns
yhfB
[SW|Categories] containing this gene/protein
[SW|biosynthesis of lipids]
The protein
Catalyzed reaction/ biological activity
Acetyl-CoA + malonyl-[acyl-carrier-protein] = acetoacyl-[acyl-carrier-protein] + CoA + CO2 (according to Swiss-Prot)
acetyl-CoA + H+ + malonyl-[ACP] --> 3-oxobutanoyl-[ACP] + CO2 + CoA (according to UniProt)
The protein
Protein family
fabH family (according to Swiss-Prot)
[SW|thiolase-like superfamily] (according to UniProt)
The protein
Paralogous protein(s)
[SW|FabHA], one of the two proteins has to be present for viability [Pubmed|17114254]
[[this]]
Expression and Regulation
Operon
''fabHB'' [Pubmed|12737802]
Expression and Regulation
Regulation
induced if the cells experience a lack of malonyl-CoA ([[protein|FapR]]) [Pubmed|12737802]
induced upon fatty acid biosynthesis inhibition [Pubmed|21383089]
Expression and Regulation
Regulatory mechanism
[[protein|FapR]]: transcription repression [Pubmed|12737802]
References
Original Publications
proteinLength
325
geneLength
978
Gene
Coordinates
1,092,770 → 1,093,747
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE10170 (Δ[[gene|fabHB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAATCACTCCTTATG, downstream forward: _UP4_TAACAAAAAAAGAACTTGTT
BKK10170 (Δ[[gene|fabHB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10170 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGAATCACTCCTTATG, downstream forward: _UP4_TAACAAAAAAAGAACTTGTT