Tue Dec 13 2016 11:16:31 GMT+0100 (CET)2025-05-23 01:00:28
description
mother cell-specific sporulation protein
mother cell-specific [SW|sporulation] protein, similar to 2-phosphosulfolactate phosphatase
locus
BSU10940
BSU_10940
ec
outlinks
bsu
BSU10940
BSU_10940
aminos
MPIAIYQGHHHSLAPADINIVIDVIRAFTVAHYAFIGGAKEILLVRTADEAFALKDTYPDYVLTGEEKGVGISGFDLDNSPKRMAGQNMTDKSLIQKTTNGVTAALGALNAKHLFVTGFSNAKTTAQHVKKLVANDCVINIVASHPSGDDDMACAEYIKGIIEGTNVVTAAEAIERIKGSSVAEKFFDCRQPLFDSEDIVYCTKELTGDFVMKVKQDGEVPTIERVII
[SW|Categories] containing this gene/protein
[SW|sporulation proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,172,650 -> 1,173,336
Expression and Regulation
Operon
''[[protein|yitC]]-[[protein|yitD]]'' [Pubmed|22383849]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigE]] [Pubmed|15383836], [[protein|SigK]] [Pubmed|15699190,15383836]
Expression and Regulation
Regulation
expressed during [SW|sporulation] in the mother cell ([[protein|SigE]], [[protein|SigK]]) [Pubmed|15699190,15383836]
expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]
References
proteinLength
228
geneLength
687
Gene
Coordinates
1,172,650 → 1,173,336
The protein
Catalyzed reaction/ biological activity
(2R)-O-phospho-3-sulfolactate + H2O --> (R)-3-sulfolactate + phosphate (according to UniProt)
The protein
Protein family
ComB family (single member, according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|1VR0] (from Clostridium acetobutylicum, 31% identity) [pubmed|16927339]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B177 (yitC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1176 NBRP B. subtilis, Japan]
BKE10940 (Δ[[gene|yitC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTACCTCTCCTTGGGC, downstream forward: _UP4_CCAACGATAGAGAGGGTCAT
BKK10940 (Δ[[gene|yitC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10940 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATACTACCTCTCCTTGGGC, downstream forward: _UP4_CCAACGATAGAGAGGGTCAT