Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)2025-05-14 22:05:06
description
ribosomal protein
ribosomal protein L22, important for folding and stabilization of the conformation of 23S rRNA
locus
BSU01210
BSU_01210
essential
no
yes
ec
outlinks
bsu
BSU01210
BSU_01210
[SW|Categories] containing this gene/protein
[SW|translation], [SW|universally conserved proteins]
Gene
Coordinates on the chromosome (coding sequence)
138,497 -> 138,838
The protein
Protein family
[SW|ribosomal protein] L22P family (according to Swiss-Prot)
universal [SW|ribosomal protein] uL22 family (single member, according to UniProt)
The protein
[SW|Interactions]
[[protein|DefA]]-[[protein|RplV]] [Pubmed|18288106]
[[protein|RplV]]-[[protein|MifM]] [Pubmed|25903689]
Expression and Regulation
Operon
''[[protein|rpsJ]]-[[protein|rplC]]-[[protein|rplD]]-[[protein|rplW]]-[[protein|rplB]]-[[protein|rpsS]]-[[protein|rplV]]-[[protein|rpsC]]-[[protein|rplP]]-[[protein|rpmC]]-[[protein|rpsQ]]-[[protein|rplN]]-[[protein|rplX]]-[[protein|rplE]]-[[protein|rpsN]]-[[protein|rpsH]]-[[protein|rplF]]-[[protein|rplR]]-[[protein|rpsE]]-[[protein|rpmD]]-[[protein|rplO]]'' [Pubmed|9371452]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] two promoters, about 140bp and 200bp upstream of the start codon [Pubmed|9371452]
Expression and Regulation
Regulation
[[protein|RelA]] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
References
proteinLength
113
geneLength
342
Gene
Coordinates
138,497 → 138,838
Gene
Phenotypes of a mutant
essential [Pubmed|28189581]
loop duplication results in increased growth rate [pubmed|30853217]
loop duplication results in reduced hyperpolarization of cells [pubmed|30853217]
loop duplication results in increased expression of [[gene|mgtE]] [pubmed|30853217]
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689]
The protein
[SW|Localization]
[SW|ribosome]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE01210 (Δ[[gene|rplV]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE01210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTAAAAGCCTCCTCTCT, downstream forward: _UP4_TCAGAAAAGAAGGAGGGATA