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Tue Dec 13 2016 11:16:37 GMT+0100 (CET)2025-06-26 05:50:37

description

two-component response regulator (OmpR family), regulation of the ABC transporter YxdL-YxdM in response to the cationic antimicrobial peptide, LL-37

two-component response regulator ([SW|OmpR family]), regulation of the ABC transporter [[protein|YxdL]]-[[protein|YxdM]] in response to the cationic antimicrobial peptide, LL-37

locus

BSU39660

BSU_39660

product

two-component response regulator (OmpR family)

two-component response regulator ([SW|OmpR family])

ec

outlinks

bsu

BSU39660

BSU_39660

aminos

MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREKPDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISARSGEMDQVMAIENGGDDYIEKPFSYDIVLAKIKSQIRRAYGEYAAKQGEKVVEYAGVQLFVERFELRFQDEKSELSKKESKLLEVLLERGEKVTSRDRLMEKTWDTDIFIDDNTLNVYITRLRKKLRELNAPVSIEAVRGEGYQLRAQS

[SW|Categories] containing this gene/protein

[SW|transcription factors and their control], [SW|resistance against toxins/ antibiotics], [SW|phosphoproteins]

Gene

Coordinates on the chromosome (coding sequence)

4,072,284 -> 4,072,973

Expression and Regulation

Operon

''[[protein|yxdJ]]-[[protein|yxdK]]'' [Pubmed|10746760]

References

10094672, 17600057, 10746760, 15289557, 21078927, 21283517, 23504016

10094672, 17600057, 10746760, 15289557, 21078927, 21283517, 23504016, 26930060

proteinLength

229

geneLength

690

Gene

Coordinates

4,072,284 → 4,072,973

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|Response regulatory domain] (aa 3-116) (according to UniProt)

The protein

Structure

[PDB|5DCL] (NisR from Streptococcus agalactiae, 41% identity)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-B702 (yxdJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1701 NBRP B. subtilis, Japan]

BKE39660 (Δ[[gene|yxdJ]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAACTGAACCACTCCCGTT, downstream forward: _UP4_GGCTACCAGCTGAGGGCGCA

BKK39660 (Δ[[gene|yxdJ]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39660 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAACTGAACCACTCCCGTT, downstream forward: _UP4_GGCTACCAGCTGAGGGCGCA