SubtiBank SubtiBank
Version comparison:

Tue Oct 25 2016 16:59:12 GMT+0200 (CEST)2025-05-10 19:39:57

locus

BSU24150

BSU_24150

ec

outlinks

bsu

BSU24150

BSU_24150

[SW|Categories] containing this gene/protein

[SW|sporulation proteins], [SW|poorly characterized/ putative enzymes]

Gene

Coordinates on the chromosome (coding sequence)

2,510,806 -> 2,511,945

The protein

Catalyzed reaction/ biological activity

Acyl-CoA ETF = 2,3-dehydroacyl-CoA reduced ETF (according to Swiss-Prot)

A + 2,3-saturated acyl-CoA --> 2,3-dehydroacyl-CoA + AH2 (according to UniProt)

The protein

Protein family

acyl-CoA dehydrogenase family (according to Swiss-Prot)

[SW|Acyl-CoA dehydrogenase family] (according to UniProt)

The protein

Paralogous protein(s)

[[protein|YngJ]], [[protein|AcdA]], [[protein|FadE]], [[protein|YotC]]

[[this]]

The protein

Structure

[PDB|3OWA] (from ''B. anthracis'', 39% identity, 55% similarity)

[PDB|3OWA] (from ''B. anthracis'', 39% identity, 55% similarity)

[PDB|4L1F] (from ''Acidaminococcus Fermentans'', 56% identity)

Expression and Regulation

Operon

''[[protein|mmgA]]-[[protein|mmgB]]-[[protein|mmgC]]-[[protein|mmgD]]-[[protein|mmgE]]-[[protein|yqiQ]]'' [Pubmed|8759838]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigE]] [Pubmed|15699190,8759838]

Expression and Regulation

Regulation

expressed early during sporulation in the mother cell ([[protein|SigE]]) [Pubmed|15699190,8759838]

repressed by glucose ([[protein|CcpA]]) [Pubmed|8759838]

Expression and Regulation

Regulatory mechanism

[[protein|CcpA]]: transcription repression [Pubmed|8759838]

References

8759838, 15699190

8759838, 15699190, 27766092

proteinLength

379

geneLength

1140

Gene

Coordinates

2,510,806 → 2,511,945

The protein

[SW|Cofactors]

FAD (according to UniProt)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE24150 (Δ[[gene|mmgC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACTCGGCCACCCCCGGAT, downstream forward: _UP4_TGATAGACAAAAAACGCAAA

BKK24150 (Δ[[gene|mmgC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24150 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACTCGGCCACCCCCGGAT, downstream forward: _UP4_TGATAGACAAAAAACGCAAA