Mon Aug 31 2015 13:57:38 GMT+0200 (CEST)2025-05-22 01:12:40
locus
BSU39360
BSU_39360
outlinks
bsu
BSU39360
BSU_39360
syns
[SW|Categories] containing this gene/protein
[SW|utilization of amino acids]
The protein
Catalyzed reaction/ biological activity
3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate = urocanate + H2O (according to Swiss-Prot)
4-imidazolone-5-propanoate --> H2O + trans-urocanate (according to UniProt)
The protein
Protein family
urocanase family (according to Swiss-Prot)
urocanase family (single member, according to UniProt)
Expression and Regulation
Operon
''[[protein|hutP]]-[[protein|hutH]]-[[protein|hutU]]-[[protein|hutI]]-[[protein|hutG]]-[[protein|hutM]]'' [Pubmed|10746760]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|8071225]
Expression and Regulation
Regulation
repressed by glucose ([[protein|CcpA]]) [Pubmed|8071225]
induced by histidine ([[protein|HutP]]) [Pubmed|8071225]
repressed during growth in the presence of branched chain amino acids ([[protein|CodY]]) [Pubmed|8682780]
Expression and Regulation
Regulatory mechanism
[[protein|CcpA]]: transcription repression [Pubmed|8071225]
[[protein|CodY]]: transcription repression [Pubmed|8682780]
[[protein|HutP]]: transcriptional antitermination at a protein-dependent [SW|RNA switch] located between ''[[protein|hutP]]'' and ''[[protein|hutH]]'' [Pubmed|8071225]
proteinLength
552
geneLength
1659
Gene
Coordinates
4,043,574 → 4,045,232
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE39360 (Δ[[gene|hutU]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGTCATATGTTCATCCCCCT, downstream forward: _UP4_ATGCAAAAATAAAGGAGTGA
BKK39360 (Δ[[gene|hutU]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AGTCATATGTTCATCCCCCT, downstream forward: _UP4_ATGCAAAAATAAAGGAGTGA