Tue Dec 06 2016 16:21:43 GMT+0100 (CET)2025-05-25 14:38:25
description
heat-shock protein (activation of DnaK)
heat-shock protein (activation of [[protein|DnaK]])
locus
BSU25480
BSU_25480
function
control of DnaK activity
control of [[protein|DnaK]] activity
ec
outlinks
bsu
BSU25480
BSU_25480
[SW|Categories] containing this gene/protein
[SW|chaperones/ protein folding], [SW|heat shock proteins]
Gene
Coordinates on the chromosome (coding sequence)
2,627,971 -> 2,628,534
The protein
Protein family
grpE family (according to Swiss-Prot)
grpE family (single member, according to UniProt)
The protein
Structure
[PDB|4ANI] ([SW|DnaK]-[SW|GrpE] complex from ''Geobacillus kaustophilus'', 70% identity) [Pubmed|22544739]
[PDB|4ANI] ([[protein|DnaK]]-[[protein|GrpE]] complex from ''Geobacillus kaustophilus'', 70% identity) [Pubmed|22544739]
Expression and Regulation
Operon
''[[protein|hrcA]]-[[protein|grpE]]-[[protein|dnaK]]-[[protein|dnaJ]]-[[protein|yqeT]]-[[protein|yqeU]]-[[protein|yqeV]]'' [Pubmed|9023197]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|1339421]
Expression and Regulation
Regulation
induced by heat shock ([[protein|HrcA]]) [Pubmed|1339421]
Expression and Regulation
Regulatory mechanism
[[protein|HrcA]]: transcription repression [Pubmed|1339421]
Labs working on this gene/protein
[SW|Wolfgang Schumann], Bayreuth University, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/schumann_research.htm Homepage]
proteinLength
187
geneLength
564
Gene
Coordinates
2,627,971 → 2,628,534
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE25480 (Δ[[gene|grpE]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE25480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTGTTCACCTCCCTCA, downstream forward: _UP4_TAATTACATAGCAGGAGGTT
BKK25480 (Δ[[gene|grpE]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK25480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTGTTCACCTCCCTCA, downstream forward: _UP4_TAATTACATAGCAGGAGGTT
labs
[SW|Wolfgang Schumann], Bayreuth University, Germany [http://www.genetik.uni-bayreuth.de/LSGenetik1/schumann_research.htm Homepage]