locus

BSU29080

BSU_29080

outlinks

bsu

BSU29080

BSU_29080

The protein

Catalyzed reaction/ biological activity

Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to Swiss-Prot)

Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine (according to UniProt)

The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate (according to UniProt)

The protein

Protein family

FPG family (according to Swiss-Prot)

FPG family (single member, according to UniProt)

Biological materials

Mutant

MGNA-A116 (mutM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/116 NBRP B. subtilis, Japan]

BKE29080 (Δ[[gene|mutM]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29080 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATCCATCACTTCCTATC, downstream forward: _UP4_TAGCATAATGCTTCATTGTC

BKK29080 (Δ[[gene|mutM]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29080 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATCCATCACTTCCTATC, downstream forward: _UP4_TAGCATAATGCTTCATTGTC

MGNA-A116 (mutM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/116 NBRP B. subtilis, Japan]

BKE29080 (Δ[[gene|mutM]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29080 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACATCCATCACTTCCTATC, downstream forward: _UP4_TAGCATAATGCTTCATTGTC

BKK29080 (Δ[[gene|mutM]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29080 BGSC] and in [SW|Jörg Stülke]'s lab, [Pubmed|28189581], upstream reverse: _UP1_CACATCCATCACTTCCTATC, downstream forward: _UP4_TAGCATAATGCTTCATTGTC

The protein

Paralogous protein(s)

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