Tue Dec 13 2016 11:16:31 GMT+0100 (CET)2025-05-14 20:21:49
title
yfmF
fecF
locus
BSU07490
BSU_07490
names
yfmF
fecF
yfmF
outlinks
bsu
BSU07490
BSU_07490
aminos
MGKLAADQLTLSYDSTVIIDGVDLKIEEGKITALIGANGCGKSTILKSLARLMAPKSGTVLLEGKDIHRQPSKEVAKKLAILPQSPQAPEGLTVEELCYFGRHPHKKLLSKHTQEDHDMVEWALEATGMIELKDRTLDALSGGQRQRAWISMALAQGTDLLLLDEPTTYLDISHQIEVLELLKKLNRDHGRTVVMVLHDLNQAAQYADYLISVLDGKIYNAGTPEDVFTQPFFREVFGLECCIMRSPIDQKPMCLPTGLCPKLRAK
[SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
822,903 -> 823,703
The protein
Protein family
[SW|ABC transporter] domain (according to Swiss-Prot)
[SW|ABC transporter superfamily] (according to UniProt)
The protein
Structure
[PDB|4G1U] (from ''Yersinia pestis'', the [SW|YfmD]-[SW|YfmE]-[SW|YfmF] complex, 32% identity) [Pubmed|23142986]
[PDB|4G1U] (from ''Yersinia pestis'', the [[protein|FecD]]-[[protein|FecE]]-[[protein|FecF]] complex, 32% identity) [Pubmed|23142986]
The protein
[SW|Localization]
associated to the membrane (via [[protein|YfmD]]-[[protein|YfmE]]) [Pubmed|10092453]
associated to the membrane (via [[protein|FecD]]-[[protein|FecE]]) [Pubmed|10092453]
The protein
[SW|Interactions]
[[protein|YfmF]]-([[protein|YfmD]]-[[protein|YfmE]])-([[protein|YfmC]]-[[protein|YhfQ]]) [Pubmed|10092453]
Expression and Regulation
Operon
''[[protein|yfmC]]-[[protein|yfmD]]-[[protein|yfmE]]-[[protein|yfmF]]'' [Pubmed|16672620]
Expression and Regulation
Regulation
induced upon iron starvation ([[protein|Fur]]) [Pubmed|16672620,12354229]
Expression and Regulation
Regulatory mechanism
[[protein|Fur]]: transcription repression [Pubmed|16672620,12354229]
References
proteinLength
266
geneLength
801
Gene
Coordinates
822,903 → 823,703
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|ABC transporter domain] (aa 4-240) (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-C244 (yfmF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2242 NBRP B. subtilis, Japan]
BKE07490 (Δ[[gene|fecF]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE07490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAGTTTTCCCATGGTATCCT, downstream forward: _UP4_TGAAAAGGAGAGGAATTCCC
BKK07490 (Δ[[gene|fecF]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK07490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAGTTTTCCCATGGTATCCT, downstream forward: _UP4_TGAAAAGGAGAGGAATTCCC