SubtiBank SubtiBank
Version comparison:

2017-10-19 11:53:582025-05-27 12:25:53

description

flagellin protein, about 20,000 subunits make up one flagellum

flagellin protein, about 12,000 subunits make up one flagellum

locus

BSU35360

BSU_35360

geneLength

912

915

function

motility and chemotaxis

[SW|motility and chemotaxis]

outlinks

bsu

BSU35360

BSU_35360

Gene

Phenotypes of a mutant

no swarming motility on B medium. [Pubmed|19202088]

not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation [Pubmed|26122431]

few hours delay in pellicle development [Pubmed|26122431]

mutant has increased fitness in planktonic culture when competed with the wild-type NCIB3610 strain [Pubmed|26122431]

increased [[protein|DegU]]-P formation, resulting in reduced [[gene|comK]] expression and strongly reduced [SW|genetic competence] [pubmed|28800172]

no swarming motility on B medium [Pubmed|19202088]

not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation [Pubmed|26122431]

few hours delay in pellicle development [Pubmed|26122431]

mutant has increased fitness in planktonic culture when competed with the wild-type NCIB3610 strain [Pubmed|26122431]

a substitution of Ala233 to Val results in straight flagella [pubmed|28800172]

The protein

Protein family

bacterial flagellin family (according to Swiss-Prot)

bacterial flagellin family (with [[protein|FlgL]] and [[protein|YvzB]], according to UniProt)

The protein

Paralogous protein(s)

[[protein|YvzB]] (C-terminal domain of Hag)

[[this]]

The protein

Structure

[PDB|3A5X] (from ''Salmonella typhimurium'', 42% identity)

the structure of flagellar filaments: [pubmed|29038601]

[PDB|3A5X] (from ''Salmonella typhimurium'', 42% identity) [pubmed|20228803]

the structure of flagellar filaments: [pubmed|29038601]

The protein

additional information

belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]

belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]

12.000 monomers make up one flagellum [pubmed|31113895]

Biological materials

Expression vector

expression in ''B. subtilis'', in [SW|pBQ200]: pGP1089, available in [SW|Jörg Stülke]'s lab

Biological materials

lacZ fusion

pGP1035 (in [[protein|pAC6]]), pGP755 (in [[protein|pAC7]]), there is also a series of promoter deletion variants in [[protein|pAC6]] and [[protein|pAC7]] [Pubmed|21856853], all available in [SW|Jörg Stülke]'s lab

pGP1035 (in [SW|pAC6]), pGP755 (in [SW|pAC7]), there is also a series of promoter deletion variants in [SW|pAC6] and [SW|pAC7] [Pubmed|21856853], all available in [SW|Jörg Stülke]'s lab

Labs working on this gene/protein

[SW|Daniel Kearns]

References

Original Publications

18566286, 26122431, 23144244, 21602220, 21856853, 2498284, 9648743, 9096206, 7708689, 19202088, 18763711, 21895793, 10809682, 19118355, 17555441, 20534509, 15378759, 29038601

18566286, 26122431, 23144244, 21602220, 21856853, 2498284, 9648743, 9096206, 7708689, 19202088, 18763711, 21895793, 10809682, 19118355, 17555441, 20534509, 15378759, 29038601, 20228803, 28800172, 29124898, 31113895

Biological materials

Expression vectors

expression in ''B. subtilis'', in [SW|pBQ200]: pGP1089, available in [SW|Jörg Stülke]'s lab

labs

[SW|Daniel Kearns]