Mon Feb 01 2016 11:06:48 GMT+0100 (CET)2025-05-22 13:11:38
locus
BSU27900
BSU_27900
outlinks
bsu
BSU27900
BSU_27900
[SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of amino acids]
Gene
Coordinates on the chromosome (coding sequence)
2,851,283 -> 2,852,140
The protein
Catalyzed reaction/ biological activity
Prephenate = phenylpyruvate
H+ + prephenate --> 3-phenylpyruvate + CO2 + H2O (according to UniProt)
Expression and Regulation
Operon
''[SW|spo0B]-[[protein|obg]]-[[protein|yszB]]-[[protein|pheA]]'' [Pubmed|22383849]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|2537815]
Expression and Regulation
Additional information
subject to feedback inhibtion by phenylalanine [PubMed|4956345]
Biological materials
Mutant
1A617 ( ''pheA''::''erm''), [Pubmed|3015878], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A617&Search=1A617 BGSC]
1A617 ( ''pheA''::''erm''), [Pubmed|3015878], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A617&Search=1A617 BGSC]
BKE27900 (Δ[[gene|pheA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GACTTTCATGACGATTTTCT, downstream forward: _UP4_TAAAAAAAGCCCACTAGAGG
BKK27900 (Δ[[gene|pheA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27900 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GACTTTCATGACGATTTTCT, downstream forward: _UP4_TAAAAAAAGCCCACTAGAGG
proteinLength
285
geneLength
858
Gene
Coordinates
2,851,283 → 2,852,140
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
Prephenate dehydratase domain (aa 2-183) (according to UniProt)
[SW|ACT domain] (aa 204-281) (according to UniProt)
The protein
Structure
[PDB|4LUB] (from ''Streptococcus mutans'', 42% identity)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]