Mon Aug 31 2015 13:56:02 GMT+0200 (CEST)2025-05-11 17:49:05
locus
BSU27870
BSU_27870
outlinks
bsu
BSU27870
BSU_27870
syns
[SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors], [SW|phosphoproteins]
The protein
Catalyzed reaction/ biological activity
L-aspartate + O2 = iminosuccinate + H2O2 (according to Swiss-Prot)
L-aspartate + O2 --> H2O2 + iminosuccinate (according to UniProt)
The protein
Protein family
NadB subfamily (according to Swiss-Prot)
FAD-dependent oxidoreductase 2 family (with [[protein|SdhA]], according to UniProt)
Expression and Regulation
Operon
''[[protein|nadB]]-[[protein|nadC]]-[[protein|nadA]]'' [Pubmed|8444804]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|8444804]
Expression and Regulation
Regulation
repressed in the presence of nicotinic acid ([[protein|NadR]]) [Pubmed|16199587]
Expression and Regulation
Regulatory mechanism
[[protein|NadR]]: transcription repression [Pubmed|16199587]
Labs working on this gene/protein
[SW|Alessandra Albertini], University of Pavia, Italy [http://www-1.unipv.it/genbiom/albertini.html homepage]
proteinLength
531
geneLength
1596
Gene
Coordinates
2,847,871 → 2,849,466
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Cofactors]
FAD (according to UniProt)
The protein
Structure
[PDB|5KXJ] (from Salmonella typhimurium, 38% identity)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE27870 (Δ[[gene|nadB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE27870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGCCATCCTCCTGTTG, downstream forward: _UP4_AGAAAAAACGAGGGGATTTG
BKK27870 (Δ[[gene|nadB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK27870 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATGCCATCCTCCTGTTG, downstream forward: _UP4_AGAAAAAACGAGGGGATTTG
labs
[SW|Alessandra Albertini], University of Pavia, Italy [http://www-1.unipv.it/genbiom/albertini.html homepage]