SubtiBank SubtiBank
Version comparison:

Mon Aug 31 2015 13:56:50 GMT+0200 (CEST)2025-05-12 05:20:24

description

choline ABC transporter (binding protein)

choline and arsenocholine [SW|ABC transporter] (binding protein)

locus

BSU33710

BSU_33710

product

choline ABC transporter (binding protein)

choline and arsenocholine [SW|ABC transporter] (binding protein)

ec

outlinks

bsu

BSU33710

BSU_33710

[SW|Categories] containing this gene/protein

[SW|ABC transporters], [SW|coping with hyper-osmotic stress], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

3,460,503 -> 3,461,423

The protein

Paralogous protein(s)

[SW|OpuCC]

[[this]]

The protein

Structure

[PDB|3R6U]

[PDB|3R6U], [PDB|6EYQ] (in complex with choline) [pubmed|21658392]

[PDB|5NXX] (in complex with arsenocholine) [pubmed|29159878]

[PDB|6EYL] (in complex with carnitine)

[PDB|6EYG] (mutant in complex with betaine)

[PDB|6EYH] (mutant in complex with dimethylsulfoniopropionate)

The protein

[SW|Localization]

associated to the membrane (via [SW|OpuBB]-[SW|OpuBD]) [Pubmed|10092453]

lipoprotein [Pubmed|10216873]

associated to the membrane (via [[protein|OpuBB]]-[[protein|OpuBD]]) [Pubmed|10092453]

lipoprotein [Pubmed|10216873]

The protein

[SW|Interactions]

[SW|OpuBA]-([SW|OpuBB]-[SW|OpuBD])-[SW|OpuBC] [Pubmed|10092453]

Expression and Regulation

Operon

''[SW|opuBA]-[SW|opuBB]-[SW|opuBC]-[SW|opuBD]'' [Pubmed|10216873]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|10216873]

Expression and Regulation

Regulation

induced by salt stress [Pubmed|10216873]

induced by choline ([[protein|GbsR]]) [Pubmed|22408163]

Expression and Regulation

Regulatory mechanism

[[protein|GbsR]]: transcription repression [Pubmed|22408163]

[[protein|OpcR]]: transcription repression [Pubmed|23960087]

[[protein|RemA]]: transcription activation [Pubmed|23646920]

References

22408163, 21366542, 21658392, 10092453, 9925583, 10216873, 21296969, 23960087, 23646920

proteinLength

306

geneLength

921

Gene

Coordinates

3,460,503 → 3,461,423

The protein

Catalyzed reaction/ biological activity

uptake of choline and arsenocholine [pubmed|29159878]

The protein

Protein family

OsmX family (with [[protein|OpuCC]], according to UniProt)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE33710 (Δ[[gene|opuBC]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE33710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTTCTTTTCATGAGCCGCC, downstream forward: _UP4_GAATCGTGAAAGGGGGAAGA

BKK33710 (Δ[[gene|opuBC]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK33710 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTTTCTTTTCATGAGCCGCC, downstream forward: _UP4_GAATCGTGAAAGGGGGAAGA

References

Reviews

27935846

References

Original publications

22408163, 21366542, 21658392, 10092453, 9925583, 10216873, 21296969, 23960087, 23646920, 28256787, 29159878, 32373088