Mon Aug 31 2015 13:55:15 GMT+0200 (CEST)2025-04-04 22:03:40
locus
BSU22340
BSU_22340
ec
outlinks
bsu
BSU22340
BSU_22340
syns
jooB, ypoB
[SW|Categories] containing this gene/protein
[SW|DNA repair/ recombination]
Gene
Phenotypes of a mutant
the mutant is sensititive to exposure to H2O2 [Pubmed|21954439]
the mutant is sensititive to exposure to H2O2 [Pubmed|21954439]
The protein
Catalyzed reaction/ biological activity
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate (according to Swiss-Prot)
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate (according to UniProt)
Expression and Regulation
Operon
''[[protein|dnaD]]-[[protein|nth]]'' [Pubmed|21954439]
Expression and Regulation
Regulation
constitutively expressed [Pubmed|21954439]
expression is transiently increased after treatment with H2O2 [Pubmed|21954439]
proteinLength
219
geneLength
660
Gene
Coordinates
2,344,755 → 2,345,414
The protein
Protein family
Nth/MutY family (with [[protein|MutY]], according to UniProt)
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
HhH domain (aa 109-128) (according to UniProt)
The protein
[SW|Cofactors]
Fe-S cluster [pubmed|29292548]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE22340 (Δ[[gene|nth]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAACACGATTGTCACCTTTT, downstream forward: _UP4_GATAAAAAAGGACTGGTGAA
BKK22340 (Δ[[gene|nth]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22340 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TAACACGATTGTCACCTTTT, downstream forward: _UP4_GATAAAAAAGGACTGGTGAA