SubtiBank SubtiBank
Version comparison:

2017-8-11 16:0:3Tue Dec 13 2016 11:16:37 GMT+0100 (CET)

proteinLength

297

geneLength

891

product

2-keto-myo-inositol dehydratase, dehydration of 2-keto-myo-inositol (2nd reaction)

2-keto-myo-inositol dehydratase,
dehydration of 2-keto-myo-inositol (2nd reaction)

Gene

Coordinates

4,078,173 → 4,079,066

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-B774 (iolE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1773 NBRP B. subtilis, Japan]

aminos

MGKNEILWGIAPIGWRNDDMPEIGAGNTLQHLLSDIVVARFQGTEVGGFFPEPAILNKELKLRNLRIAGKWFSSFILRDGLGEAAKTFTLHCEYLQQVNADVAVVSEQTYSVQSLEKNVFTEKPHFTDDEWERLCEGLNHLGEIAAQHGLKLVYHHHLGTGVQTAEEVDRLMAGTDPAHVHLLYDTGHAYISDGDYMGMLEKHIGRIKHVHFKDARLNVMEQCRLEGQSFRQSFLKGMFTVPGDGCIDFREVYQLLLKHSYSGWIVIEAEQDPDVANPLEYALIARNYIDQQLLDLA

[SW|Categories] containing this gene/protein

[SW|utilization of specific carbon sources]

Gene

Coordinates on the chromosome (coding sequence)

4,078,173 -> 4,079,066

Expression and Regulation

Operon

''[[protein|iolA]]-[[protein|iolB]]-[[protein|iolC]]-[[protein|iolD]]-[[protein|iolE]]-[[protein|iolF]]-[[protein|iolG]]-[[protein|iolH]]-[[protein|iolI]]-[[protein|iolJ]]'' [Pubmed|9226270]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|9226270]

Expression and Regulation

Regulation

repressed by glucose ([[protein|CcpA]]) [Pubmed|10666464]

induced by inositol ([[protein|IolR]]) [Pubmed|9887260,9226270]

Expression and Regulation

Regulatory mechanism

[[protein|IolR]]: transcription repression [Pubmed|9887260,9226270]

[[protein|CcpA]]: transcription repression [Pubmed|10666464]