Mon Aug 31 2015 13:54:38 GMT+0200 (CEST)2025-04-11 08:46:41
locus
BSU18300
BSU_18300
ec
outlinks
bsu
BSU18300
BSU_18300
[SW|Categories] containing this gene/protein
[SW|miscellaneous metabolic pathways], [SW|biosynthesis of antibacterial compounds], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,960,198 -> 1,964,037
The protein
Protein family
UPF0713 family (according to Swiss-Prot)
[SW|ATP-dependent AMP-binding enzyme family] (according to UniProt)
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cytoplasm (according to UniProt)
Expression and Regulation
Operon
''[[protein|ppsA]]-[[protein|ppsB]]-[[protein|ppsC]]-[[protein|ppsD]]-[[protein|ppsE]]'' [Pubmed|20817675]
Expression and Regulation
Regulatory mechanism
[[protein|AbrB]]: transcription repression [Pubmed|20817675]
References
proteinLength
1279
geneLength
3840
Gene
Coordinates
1,960,198 → 1,964,037
The protein
Paralogous protein(s)
[[this]]
reiterated [[protein|SrfAC]]-like proteins: [[protein|DhbF]], [[protein|PpsA]], [[protein|PpsB]], [[protein|PpsC]], [[protein|PpsD]], [[protein|SrfAA]], [[protein|SrfAB]]
partial match (more than 1,000 amino acids): [[protein|PksJ]], [[protein|PksN]]
The protein
[SW|Domains]
[SW|Carrier domain] (aa 975-1050) (according to UniProt)
The protein
Structure
[PDB|2VSQ] ([[protein|SrfAC]], 40% identity) [pubmed|18583577]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE18300 (Δ[[gene|ppsE]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18300 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTCTGCACCTTTCTTCACGG, downstream forward: _UP4_TAAAGCGGATTAGCGGACAG
BKK18300 (Δ[[gene|ppsE]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18300 BGSC], [Pubmed|28189581], upstream reverse: _UP1_GTCTGCACCTTTCTTCACGG, downstream forward: _UP4_TAAAGCGGATTAGCGGACAG