2017-8-11 16:0:3Tue Dec 13 2016 11:16:36 GMT+0100 (CET)
proteinLength
344
geneLength
1032
Gene
Coordinates
3,521,111 → 3,522,145
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A067 (yveR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/67 NBRP B. subtilis, Japan]
aminos
METPAVSLLVAVYNTETYIRTCLESLRNQTMDNIEIIIVNDGSADASPDIAEEYAKMDNRFKVIHQENQGLGAVRNKGIEAARGEFIAFIDSDDWIEPDYCEQMLRTAGDETDLVICNYAAEFEDTGKTMDSDIAQTYQDQPKEHYIKALFEGKVRGFSWNKLYRRSMIEAHRLSFPLRGELEHVEDQFFSFRAHFFARSVSYVKTPLYHYRIHLSSIVQRYQKKLFESGLALYETNAAFLQENNKLEEYRKELDTFIVLHSSICMLNEWKTSGSRRLFEKLRNVGVICADPVFQESLSKTGTAPFDAKRSCLLLMAKYRMIPFVAMASAVYQRVIEYKMRNRG
[SW|Categories] containing this gene/protein
[SW|biofilm formation]
Gene
Coordinates on the chromosome (coding sequence)
3,521,111 -> 3,522,145
Expression and Regulation
Operon
''[[protein|epsA]]-[[protein|epsB]]-[[protein|epsC]]-[[protein|epsD]]-[[protein|epsE]]-[[protein|epsF]]-[[protein|epsG]]-[[protein|epsH]]-[[protein|epsI]]-[[protein|epsJ]]-[[protein|epsK]]-[[protein|epsL]]-[[protein|epsM]]-[[protein|epsN]]-[[protein|epsO]]'' [Pubmed|15661000]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|15661000]
Expression and Regulation
Regulation
repressed by [[protein|SinR]] [Pubmed|15661000]
Expression and Regulation
Regulatory mechanism
[[protein|SinR]]: transcription anti-activation (prevents binding of [[protein|RemA]]) [Pubmed|23646920]
[[protein|RemA]]: transcription activation [Pubmed|23646920]
[[protein|AbrB]]: transcription repression [Pubmed|20817675]
Expression and Regulation
Additional information
induction by sequestration of [[protein|SinR]] by [[protein|SinI]] or [[protein|SlrA]] [PubMed|15661000,19788541]
the '[[protein|epsA]]-[[protein|epsB]]-[[protein|epsC]]-[[protein|epsD]]-[[protein|epsE]]-[[protein|epsF]]-[[protein|epsG]]-[[protein|epsH]]-[[protein|epsI]]-[[protein|epsJ]]-[[protein|epsK]]-[[protein|epsL]]-[[protein|epsM]]-[[protein|epsN]]-[[protein|epsO]]' operon is not expressed in a '[[protein|ymdB]]' mutant [PubMed|21856853]
the amount of the mRNA is substantially decreased upon depletion of [[Rny|RNase Y]] (this is likely due to the increased stability of the '[[protein|sinR]]' mRNA) [PubMed|21815947]
the [[EAR riboswitch]] (eps-associated [[RNA switch]]) located between' [[protein|epsB]]' and '[[protein|epsC]]' mediates processive antitermination and allows expression of the long eps operon [PubMed|20374491]