Mon Aug 31 2015 13:54:20 GMT+0200 (CEST)2025-05-22 14:39:36
locus
BSU16400
BSU_16400
ec
outlinks
bsu
BSU16400
BSU_16400
[SW|Categories] containing this gene/protein
[SW|motility and chemotaxis], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,709,747 -> 1,710,847
The protein
Protein family
GTP-binding [[protein|SRP]] family (according to Swiss-Prot)
GTP-binding SRP family (with [[protein|Ffh]] and [[protein|FtsY]], according to UniProt)
The protein
Structure
[PDB|2PX3] (complexed with GTP-Mg2
[PDB|3SYN] (complex with its activator [[protein|YlxH]]) [Pubmed|22056770]
[PDB|2PX3] (complexed with GTP-Mg2+) [Pubmed|17699634]
[PDB|3SYN] (complex with its activator [[protein|FlhG]]) [Pubmed|22056770]
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cell membrane (according to UniProt)
The protein
[SW|Interactions]
[[protein|FlhG]]-[[protein|FlhF]] ([[protein|FlhG]] binds the GTP-bound homodimer of [[protein|FlhF]]) [Pubmed|22056770]
Expression and Regulation
Operon
part of the [[fla-che operon]]
''[[protein|flgB]]-[[protein|flgC]]-[[protein|fliE]]-[[protein|fliF]]-[[protein|fliG]]-[[protein|fliH]]-[[protein|fliI]]-[[protein|fliJ]]-[[protein|ylxF]]-[[protein|fliK]]-[[protein|flgD]]-[[protein|flgE]]-[[protein|fliL]]-[[protein|fliM]]-[[protein|fliY]]-[[protein|cheY]]-[[protein|fliZ]]-[[protein|fliP]]-[[protein|fliQ]]-[[protein|fliR]]-[[protein|flhB]]-[[protein|flhA]]-[[protein|flhF]]-[[protein|flhG]]-[[protein|cheB]]-[[protein|cheA]]-[[protein|cheW]]-[[protein|cheC]]-[[protein|cheD]]-[[protein|sigD]]-[[protein|swrB]]'' [Pubmed|9657996,8157612,15175317]
''[[protein|ylxF]]-[[protein|fliK]]-[[protein|flgD]]-[[protein|flgE]]-[[protein|fliL]]-[[protein|fliM]]-[[protein|fliY]]-[[protein|cheY]]-[[protein|fliZ]]-[[protein|fliP]]-[[protein|fliQ]]-[[protein|fliR]]-[[protein|flhB]]-[[protein|flhA]]-[[protein|flhF]]-[[protein|flhG]]-[[protein|cheB]]-[[protein|cheA]]-[[protein|cheW]]-[[protein|cheC]]-[[protein|cheD]]-[[protein|sigD]]-[[protein|swrB]]'' [Pubmed|20233303]
Expression and Regulation
[SW|Sigma factor]
''[[protein|flgB]]'': [[protein|SigA]] [Pubmed|9657996], [[protein|SigD]] [Pubmed|9657996]
''[[protein|ylxF]]'': [[protein|SigD]] [Pubmed|20233303]
Expression and Regulation
Regulation
see [[fla-che operon]]
Expression and Regulation
Regulatory mechanism
see [[fla-che operon]]
Biological materials
Mutant
1A925 ( ''flhF''::''cat''), [Pubmed|15317803], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A925&Search=1A925 BGSC]
1A925 ( ''flhF''::''cat''), [Pubmed|15317803], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A925&Search=1A925 BGSC]
BKE16400 (Δ[[gene|flhF]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAAATATCCACCACTCC, downstream forward: _UP4_CTGTGCAGATGAACAGATAT
BKK16400 (Δ[[gene|flhF]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAAATATCCACCACTCC, downstream forward: _UP4_CTGTGCAGATGAACAGATAT
References
Original Publications
proteinLength
366
geneLength
1101
Gene
Coordinates
1,709,747 → 1,710,847
Gene
Phenotypes of a mutant
inactivation of ''[[gene|flhF]]'' confers resistance to high concentrations of Zn(II) [Pubmed|27935957]
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]