SubtiBank SubtiBank
Version comparison:

2017-06-06 08:58:17Sat Jun 25 2016 16:04:17 GMT+0200 (CEST)

proteinLength

249

geneLength

747

function

cleaves both 5- and 3-sites of the small cytoplasmic RNA precursor (scr)

cleaves both 5- and 3-sites
of the small cytoplasmic RNA precursor (scr)

Gene

Coordinates

1,665,710 → 1,666,459

Gene

Phenotypes of a mutant

essential [Pubmed|23300471,12682299,11123676]

the ''[[gene|rnc]]'' gene can be deleted in strains cured of the [SW|Skin element] and [[SPß prophage]] (or upon deletion of the toxin genes ''[[gene|txpA]]'' and ''[[gene|yonT]]'') [Pubmed|23300471]

essential [Pubmed|23300471,12682299,11123676]

the ''[[protein|rnc]]'' gene can be deleted in strains cured of the [SW|Skin element] and [[SPß prophage]] (or upon deletion of the toxin genes ''[[protein|txpA]]'' and ''[[protein|yonT]]'') [Pubmed|23300471]

The protein

Catalyzed reaction/ biological activity

Endonucleolytic cleavage of double-stranded RNA to 5'-phosphomonoester (according to Swiss-Prot)

cleaves both 5'- and 3'-sites of the small cytoplasmic RNA precursor (''[[gene|scr]]'')

degradation of ''[[gene|txpA]]'' mRNA-[[protein|FFCE5AD9E04E6D5F7970E89781C545E7DBDF45F0]] RNA duplex (encoded on the [SW|Skin element]) [Pubmed|23300471]

degradation of ''[[gene|yonT]]'' mRNA-''[[gene|SR6]]'' RNA duplex (encoded on the [[SP-beta prophage]]) [Pubmed|23300471]

degradation of the ''[[gene|roxS]]''-''[[gene|ytdI]]'' and ''[[gene|roxS]]-[[gene|sucC]]'' RNA duplexes [Pubmed|25643072]

Endonucleolytic cleavage of double-stranded RNA to 5'-phosphomonoester (according to Swiss-Prot)

cleaves both 5'- and 3'-sites of the small cytoplasmic RNA precursor (''[[protein|scr]]'')

degradation of ''[[protein|txpA]]'' mRNA-[[protein|RatA]] RNA duplex (encoded on the [SW|Skin element]) [Pubmed|23300471]

degradation of ''[[protein|yonT]]'' mRNA-''[[protein|as-yonT]]'' RNA duplex (encoded on the [[SP-beta prophage]]) [Pubmed|23300471]

degradation of the ''[[protein|roxS]]''-''[SW|ppnKB]'' and ''[[protein|roxS]]-[[protein|sucC]]'' RNA duplexes [Pubmed|25643072]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

[SW|Categories] containing this gene/protein

[SW|RNases], [SW|translation], [SW|protein secretion], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence)

1,665,710 -> 1,666,459

Expression and Regulation

Operon

''[[protein|rnc]]-[[protein|smc]]-[[protein|ftsY]]'' [Pubmed|11021934]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|11021934]

Expression and Regulation

Regulation

[[protein|RelA]] dependent downregulation (Class I) during stringent response [Pubmed|11948165]