SubtiBank SubtiBank
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Mon Aug 31 2015 13:54:36 GMT+0200 (CEST)2025-05-21 11:44:56

description

amino acid carrier protein

putative glutamine transporter

locus

BSU18120

BSU_18120

function

amino acid uptake

uptake of glutamine

product

amino acid carrier protein

putative glutamine transporter

ec

outlinks

bsu

BSU18120

BSU_18120

syns

[SW|Categories] containing this gene/protein

[SW|transporters/ other], [SW|putative amino acid transporter], [SW|membrane proteins]

The protein

Protein family

sodium:alanine (SAF) symporter family (according to Swiss-Prot)

[SW|Alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family] (according to UniProt)

Expression and Regulation

Regulation

repressed in the absence of good nitrogen sources (glutamine or ammonium) ([[protein|TnrA]]) [Pubmed|12823818]

Expression and Regulation

Regulatory mechanism

[[protein|TnrA]]: transcription repression [Pubmed|12823818]

Biological materials

Mutant

GP1888 (tet) available in [SW|Jörg Stülke]'s lab

GP1888 (Δ[[gene|alsT]]::tet), available in [SW|Jörg Stülke]'s lab [pubmed|32743959]

BKE18120 (Δ[[gene|alsT]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE18120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTACCTCCCGTTTTC, downstream forward: _UP4_TAATATAAATATAAAACAAA

BKK18120 (Δ[[gene|alsT]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK18120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTTACCTCCCGTTTTC, downstream forward: _UP4_TAATATAAATATAAAACAAA

References

12823818, 25755103, 18763711

12823818, 25755103, 18763711, 29326168, 28835263, 31997474, 30659158

proteinLength

465

geneLength

1398

Gene

Coordinates

1,938,925 → 1,940,322

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|6CSE] (sodium/alanine symporter from Methanococcus maripaludis S2, 36% identity) [pubmed|30659158]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]