SubtiBank SubtiBank
Version comparison:

Tue Dec 13 2016 11:16:37 GMT+0100 (CET)2025-05-10 11:27:23

locus

BSU38970

BSU_38970

ec

outlinks

bsu

BSU38970

BSU_38970

aminos

MRKQVALVTGAAGGIGFEIAREFAREGASVIVSDLRPEACEKAASKLAEEGFDAAAIPYDVTKEAQVADTVNVIQKQYGRLDILVNNAGIQHVAPIEEFPTDTFEQLIKVMLTAPFIAMKHVFPIMKKQQFGRIINIASVNGLVGFAGKSAYNSAKHGVIGLTKVGALEGAPHGITVNALCPGYVDTQLVRNQLSDLSKTRNVPYDSVLEQVIFPLVPQKRLLSVKEIADYAVFLASEKAKGVTGQAVVLDGGYTAQ

[SW|Categories] containing this gene/protein

[SW|utilization of specific carbon sources], [SW|sporulation proteins]

Gene

Coordinates on the chromosome (coding sequence)

4,000,539 -> 4,001,312

The protein

Protein family

short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

[SW|Short-chain dehydrogenases/reductases (SDR) family] (according to UniProt)

Expression and Regulation

Operon

''[[protein|hbuT]]-[[protein|scoA]]-[[protein|scoB]]-[[protein|yxjF]]'' [Pubmed|10746760]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigE]] [Pubmed|12662922]

Expression and Regulation

Regulation

repressed by glucose (4-fold) ([[protein|CcpA]]) [Pubmed|12850135,10666464]

expressed early during sporulation in the mother cell ([[protein|SigE]]) [Pubmed|12662922]

Expression and Regulation

Regulatory mechanism

[[protein|CcpA]]: transcription repression [Pubmed|12850135,10666464]

Biological materials

Mutant

GP1112 (spc), available in [SW|Stülke] lab

MGNA-B730 (yxjF::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1729 NBRP B. subtilis, Japan]

GP1112 (spc), available in [SW|Stülke] lab

BKE38970 (Δ[[gene|yxjF]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE38970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAACACCTTCCCAT, downstream forward: _UP4_TGACATAAAAAACACACTTG

BKK38970 (Δ[[gene|yxjF]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK38970 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAAACACCTTCCCAT, downstream forward: _UP4_TGACATAAAAAACACACTTG

proteinLength

257

geneLength

774

Gene

Coordinates

4,000,539 → 4,001,312

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|2YZ7] (from Alcaligenes Faecalis 42% identity)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]