Mon May 30 2016 11:06:30 GMT+0200 (CEST)2025-05-19 00:42:04
description
oligopeptide ABC transporter (permease)
oligopeptide [SW|ABC transporter] (permease)
locus
BSU11440
BSU_11440
function
initiation of sporulation, competence development
initiation of [SW|sporulation], competence development
product
oligopeptide ABC transporter (permease)
oligopeptide [SW|ABC transporter] (permease)
ec
outlinks
bsu
BSU11440
BSU_11440
[SW|Categories] containing this gene/protein
[SW|ABC transporters], [SW|utilization of nitrogen sources other than amino acids], [SW|genetic competence], [SW|phosphorelay], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,221,594 -> 1,222,529
The protein
Protein family
ABC transmembrane type-1 domain (according to Swiss-Prot)
[SW|Binding-protein-dependent transport system permease family] (according to UniProt)
[SW|OppBC subfamily] (according to UniProt)
The protein
[SW|Interactions]
([[protein|OppD]]-[[protein|OppF]])-([[protein|OppB]]-[[protein|OppC]])-[[protein|OppA]] [Pubmed|10092453]
Expression and Regulation
Operon
''[[protein|oppA]]-[[protein|oppB]]-[[protein|oppC]]-[[protein|oppD]]-[[protein|oppF]]'' [Pubmed|1901616]
Expression and Regulation
Regulation
expressed in the absence of good nitrogen sources (glutamine or ammonium) ([[protein|TnrA]]) [Pubmed|12823818]
repressed during exponential growth ([[protein|ScoC]]) [Pubmed|10383984]
Expression and Regulation
Regulatory mechanism
[[protein|TnrA]]: transcription activation [Pubmed|12823818]
[[protein|ScoC]]: transcription repression [Pubmed|10383984]
[[protein|CodY]]: transcription repression, no derepression occurs, however, in a ''[[protein|codY]]'' mutant, due to increased repression by [[protein|ScoC]] [Pubmed|25966844]
Biological materials
Mutant
GP2063 (''[[protein|oppB]]''::''spc''), available in [SW|Jörg Stülke]'s lab
GP2097 (D(''[[protein|oppA]]-[[protein|oppB]]-[[protein|oppC]]-[[protein|oppD]]-[[protein|oppF]]'')::''aphA3''), available in [SW|Jörg Stülke]'s lab
GP2063 (''[[gene|oppB]]''::''spc''), available in [SW|Jörg Stülke]'s lab
GP2097 (D(''[[gene|oppA]]-[[gene|oppB]]-[[gene|oppC]]-[[gene|oppD]]-[[gene|oppF]]'')::''aphA3''), available in [SW|Jörg Stülke]'s lab
BKE11440 (Δ[[gene|oppB]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11440 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGGGGGAACACCTCCATG, downstream forward: _UP4_AAAGCAAAGAAAGGAGCCTA
BKK11440 (Δ[[gene|oppB]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11440 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGGGGGAACACCTCCATG, downstream forward: _UP4_AAAGCAAAGAAAGGAGCCTA
References
proteinLength
311
geneLength
936
Gene
Coordinates
1,221,594 → 1,222,529
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|ABC transmembrane type-1 domain] (aa 94-295) (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]