Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)2025-05-09 12:53:31
locus
BSU10490
BSU_10490
ec
outlinks
subtilist
gene_detail+BG12674
gene_detail BG12674
outlinks
bsu
BSU10490
BSU_10490
syns
yhjF
[SW|Categories] containing this gene/protein
[SW|protein secretion], [SW|membrane proteins]
The protein
Catalyzed reaction/ biological activity
Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins (according to Swiss-Prot)
Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins (according to UniProt)
The protein
Protein family
peptidase S26 family (according to Swiss-Prot)
[SW|peptidase S26 family] (according to Uniprot)
The protein
Paralogous protein(s)
[[protein|SipS]], [[protein|SipT]], [[protein|SipU]]
[[this]]
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
cell membrane (according to UniProt)
Expression and Regulation
Operon
''[[protein|yhjE]]-[[protein|sipV]]'' (according to [http://dbtbs.hgc.jp/COG/prom/yhjE-sipV.html DBTBS])
Expression and Regulation
Regulation
induced upon DNA damage ([[protein|LexA]]) [Pubmed|16267290]
Expression and Regulation
Regulatory mechanism
[[protein|LexA]]: transcription repression [Pubmed|16267290]
Labs working on this gene/protein
[SW|Jan Maarten van Dijl], Groningen, Netherlands
References
Original publications
proteinLength
168
geneLength
507
Gene
Coordinates
1,122,175 1,122,681
The protein
Structure
[PDB|4NV4] (from B. anthracis, 47% identity)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE10490 ([[gene|sipV]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE10490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTACTGTCTCCCTCCA, downstream forward: _UP4_TAAAAAGACGCTAATTGAAG
BKK10490 ([[gene|sipV]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK10490 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTACTGTCTCCCTCCA, downstream forward: _UP4_TAAAAAGACGCTAATTGAAG
labs
[SW|Jan Maarten van Dijl], Groningen, Netherlands