Tue Dec 13 2016 11:16:31 GMT+0100 (CET)2025-05-30 09:52:21
locus
BSU06360
BSU_06360
outlinks
bsu
BSU06360
BSU_06360
aminos
MTKLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTAEEIKKMNPKGIILSGGPNSVYDENSFRCDEKIFELDIPVLGICYGMQLMTHYLGGKVEAASQREYGKANIRIEGTPDLFRDLPNEQVVWMSHGDLVVEVPEGFTVDATSHHCPNSAMSKADKKWYGVQFHPEVRHSEYGNDLLKNFVFGVCECEGEWSMENFIEIEMQKIRETVGDKQVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNVIKVDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDEADKLKGIDYLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGIPDEIVWRQPFPGPGLGIRVLGEVTEEKLEIVRESDAILREEIANHGLERDIWQYFTVLPDIRSVGVMGDARTYDYTIGIRAVTSIDGMTSDWARIPWDVLEVISTRIVNEVKHINRVVYDITSKPPATIEWE
[SW|Categories] containing this gene/protein
[SW|biosynthesis/ acquisition of nucleotides], [SW|most abundant proteins]
Gene
Coordinates on the chromosome (coding sequence)
692,740 -> 694,281
The protein
Catalyzed reaction/ biological activity
ATP xanthosine 5'-phosphate L-glutamine H2O = AMP diphosphate GMP L-glutamate (according to Swiss-Prot)
ATP + H2O + L-glutamine + XMP --> AMP + diphosphate + GMP + 2 H+ + L-glutamate (according to UniProt)
Expression and Regulation
Operon
''guaA'' [Pubmed|1312531]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|1312531]
Expression and Regulation
Additional information
term-seq has identified a potential novel regulatory RNA element including an intrinsic transcription terminator upstream of ''guaA'' [Pubmed|27120414]
belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]
References
Original publications
proteinLength
513
geneLength
1542
Gene
Coordinates
692,740 694,281
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|Glutamine amidotransferase type-1 domain] (aa 8-198) (according to UniProt)
GMPS ATP-PPase domain (aa 199-388) (according to UniProt)
The protein
additional information
belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A918 (yebB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/918 NBRP B. subtilis, Japan]
BKE06360 ([[gene|guaA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE06360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTGTCACCTAATCTC, downstream forward: _UP4_TAAGAATCAATTAATGGAAA
BKK06360 ([[gene|guaA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK06360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTGTCACCTAATCTC, downstream forward: _UP4_TAAGAATCAATTAATGGAAA