SubtiBank SubtiBank
Version comparison:

Tue Dec 13 2016 11:16:31 GMT+0100 (CET)2025-05-11 13:09:22

locus

BSU04560

BSU_04560

outlinks

bsu

BSU04560

BSU_04560

aminos

MYGGKSAEHNVSLQTALAVIKALNTEKFDIHPIYITEKGEWVRGARLTEPVSNVKMLQFEQGGSAFSPAALNQEMFPQEASQQNEAIDVVFPLLHGPNGEDGTIQGMLELLNIPYVGNGVLASSAGMDKVVMKHLFAQVGLAQAKYAAFLKKDWTRSPKESCEEVEQELGYPCFVKPANLGSSVGISKCRNREELQKAFELAFQYDRKVVVEEGINGREIEIGVLGNDDPKCSVVGEIAPKTDFYDYKAKYEDGDTDLMIPAIVTDEEYATISDMAIKAFKAIDGSGLVRADFFLTADGEVLINEVNTMPGFTPFSMFPLLWKEAGVEYADLIEQLVELAKERHAEKQLIKHTF

[SW|Categories] containing this gene/protein

[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence)

508,248 -> 509,312

The protein

Catalyzed reaction/ biological activity

ATP 2 D-alanine = ADP phosphate D-alanyl-D-alanine (according to Swiss-Prot)

ATP + 2 D-alanine --> ADP + phosphate + D-alanyl-D-alanine (according to UniProt)

The protein

Protein family

ATP-grasp domain (according to Swiss-Prot)

D-alanine--D-alanine ligase family (single member, according to UniProt)

Expression and Regulation

Operon

''[SW|ddl]-[SW|murF]'' [Pubmed|22383849]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigM]] [Pubmed|18179421]

Expression and Regulation

Regulation

expression is reduced in a [[protein|SigV]] mutant [Pubmed|21926231]

References

18179421

18179421, 29794222

proteinLength

354

geneLength

1065

Gene

Coordinates

508,248 509,312

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|ATP-grasp doamin] (aa 133-338) (according to UniProt)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

MGNA-C104 (ddlA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2102 NBRP B. subtilis, Japan]