Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)2025-04-04 13:19:45
description
ATPase, spore coat morphogenetic protein, anchors the spore coat to the spore surface via SpoVM
ATPase, spore coat morphogenetic protein, anchors the spore coat to the spore surface via [[protein|SpoVM]]
locus
BSU22800
BSU_22800
function
spore cortex formation and coat assembly
initiation of spore coat assembly
ec
outlinks
bsu
BSU22800
BSU_22800
[SW|Categories] containing this gene/protein
[SW|sporulation proteins]
The protein
Catalyzed reaction/ biological activity
uses ATP hydrolysis to drive self-assembly into static filaments [Pubmed|23267091]
ATP hydrolysis drives polymerization of a nucleotide-free filament [Pubmed|23267091]
ploymerization depends on a critical threshold concentration of SpoIVA that is only achieved once the protein is recruited to the surface of the developing spore [Pubmed|23267091]
uses ATP hydrolysis to drive self-assembly into static filaments [Pubmed|23267091]
ATP hydrolysis drives polymerization of a nucleotide-free filament [Pubmed|23267091]
ploymerization depends on a critical threshold concentration of SpoIVA that is only achieved once the protein is recruited to the surface of the developing spore [Pubmed|23267091]
ATP + H2O --> ADP + H+ + phosphate (according to UniProt)
The protein
[SW|Interactions]
[SW|SpoIVA]-[SW|SpoVID] [Pubmed|19702880,22262582]
[SW|SpoIVA]-[[protein|SafA]] [Pubmed|19702880,22262582]
[SW|SpoIVA]-[SW|SpoVM]-[SW|SpoVID] [Pubmed|19775244]
Expression and Regulation
Operon
''spoIVA'' [Pubmed|1729246]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigE]] [Pubmed|1729246,15699190]
Expression and Regulation
Regulation
expressed early during sporulation in the mother cell ([[protein|SigE]], [SW|SpoIIID]) [Pubmed|1729246,15699190,15383836]
Expression and Regulation
Regulatory mechanism
[SW|SpoIIID]: transcription repression [Pubmed|15383836]
References
Reviews
References
Original publications
proteinLength
492
geneLength
1479
Gene
Coordinates
2,386,195 2,387,673
The protein
Paralogous protein(s)
[[this]]
The protein
Modification
phosphorylated on Arg-454 [pubmed|31221751]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE22800 ([[gene|spoIVA]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22800 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGTGATCCCCTCCCGGAC, downstream forward: _UP4_TAATACCGGTAGACCTCTTT
BKK22800 ([[gene|spoIVA]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22800 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAGTGATCCCCTCCCGGAC, downstream forward: _UP4_TAATACCGGTAGACCTCTTT