2018-09-21 09:57:452025-05-30 08:38:38
locus
BSU40510
BSU_40510
geneLength
1977
1980
outlinks
bsu
BSU40510
BSU_40510
Gene
Coordinates
4,163,643 → 4,165,622
4,163,643 4,165,622
The protein
Catalyzed reaction/ biological activity
cyclic dinucleotide phosphodiesterase, hydrolysis of cyclic di-AMP [Pubmed|19901023]
cyclic dinucleotide phosphodiesterase, hydrolysis of cyclic di-AMP [Pubmed|19901023]
3',3'-c-di-AMP + H2O --> 5'-O-phosphonoadenylyl-(3'→5')-adenosine + H+ (according to UniProt)
Biological materials
Mutant
MGNA-B834 (yybT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1833 NBRP B. subtilis, Japan]
GP998 (''[[gene|gdpP]]''::''spc''), available in [SW|Jörg Stülke]'s lab [Pubmed|23192352]
GP2040 (''[[gene|gdpP]]''::''spc'' ''[[gene|pgpH]]''::''erm'' without terminator, available in [SW|Jörg Stülke]'s lab) [Pubmed|26240071]
BKE40510 (Δ[[gene|gdpP]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTATCACTCCCCACC, downstream forward: _UP4_AGATGAAGGTTATTTTCTTA
BKK40510 (Δ[[gene|gdpP]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTATCACTCCCCACC, downstream forward: _UP4_AGATGAAGGTTATTTTCTTA
MGNA-B834 (yybT::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1833 NBRP B. subtilis, Japan]
GP998 (''[[gene|gdpP]]''::''spc''), available in [SW|Jörg Stülke]'s lab [Pubmed|23192352]
GP2040 (''[[gene|gdpP]]''::''spc'' ''[[gene|pgpH]]''::''erm'' without terminator, available in [SW|Jörg Stülke]'s lab) [Pubmed|26240071]
BKE40510 ([[gene|gdpP]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE40510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTATCACTCCCCACC, downstream forward: _UP4_AGATGAAGGTTATTTTCTTA
BKK40510 ([[gene|gdpP]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK40510 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCTATCACTCCCCACC, downstream forward: _UP4_AGATGAAGGTTATTTTCTTA
References
Reviews
The protein
Protein family
GdpP/PdeA phosphodiesterase family (single member, according to UniProt)
The protein
[SW|Localization]
cell membrane (according to UniProt)
labs
[SW|Jörg Stülke], University of Göttingen, Germany [http://genmibio.uni-goettingen.de Homepage]