SubtiBank SubtiBank
Version comparison:

Wed Aug 24 2016 13:22:41 GMT+0200 (CEST)2025-05-16 07:58:02

locus

BSU28430

BSU_28430

ec

outlinks

bsu

BSU28430

BSU_28430

[SW|Categories] containing this gene/protein

[SW|carbon core metabolism], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence)

2,905,571 -> 2,906,332

The protein

Catalyzed reaction/ biological activity

Succinate acceptor = fumarate reduced acceptor (according to Swiss-Prot)

quinone + succinate --> quinol + fumarate (according to UniProt)

The protein

Protein family

succinate dehydrogenase/fumarate reductase iron-sulfur protein family (according to Swiss-Prot)

succinate dehydrogenase/fumarate reductase iron-sulfur protein family (single member, according to UniProt)

The protein

[SW|Cofactors]

[3 Fe- 4 S] cluster

Fe-S cluster [pubmed|29292548]

The protein

Structure

[PDB|1NEK] (''E. coli'')

[PDB|1NEK] (''E. coli'') [pubmed|12560550]

The protein

[SW|Interactions]

[[protein|SdhA]]-[[protein|SdhB]], [[protein|SdhB]]-[[protein|SdhC]] (as part of the [[protein|SdhC]]-[[protein|SdhB]]-[[protein|SdhA]] complex)

part of a [SW|respiratory supercomplex] [Pubmed|23880299]

Expression and Regulation

Operon

''[[protein|sdhC]]''-''[[protein|sdhA]]''-''[[protein|sdhB]]'' [Pubmed|3036777]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|2495271]

Expression and Regulation

Regulation

constitutive

part of the iron sparing response ([[protein|FsrA]]) [Pubmed|22389480]

Expression and Regulation

Regulatory mechanism

[[protein|FsrA]]: translation inhibition [Pubmed|22389480]

Biological materials

Mutant

GP792 (''[[protein|sdhC]]-[[protein|sdhA]]-[[protein|sdhB]]''::''phleo''), available in [SW|Jörg Stülke]'s lab

GP792 ∆(''[[gene|sdhC]]-[[gene|sdhA]]-[[gene|sdhB]]'')::''phleo'', available in [SW|Jörg Stülke]'s lab

GP2342 ∆(''[[gene|sdhC]]-[[gene|sdhA]]-[[gene|sdhB]]'')::''kan'', Cre-recombinase is integrated in ''[[gene|sacA]]'', available in [SW|Jörg Stülke]'s lab

GP2343 ∆(''[[gene|sdhC]]-[[gene|sdhA]]-[[gene|sdhB]]'')::''lox72'', Cre-recombinase is integrated in ''[[gene|sacA]]'', available in [SW|Jörg Stülke]'s lab

BKE28430 ∆([[gene|sdhB]])::erm trpC2 available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TATGGTTTTTTGTTCACTCA, downstream forward: _UP4_TAAGAAGAAAAAACCTCTTC

BKK28430 ∆([[gene|sdhB]])::kan trpC2 available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28430 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TATGGTTTTTTGTTCACTCA, downstream forward: _UP4_TAAGAAGAAAAAACCTCTTC

References

Original publications

1707123, 6401289, 1324713, 3036777, 2495271, 3027051, 7748886, 2837411, 12560550, 3910107, 6799760, 22389480, 23880299

1707123, 6401289, 1324713, 3036777, 2495271, 3027051, 7748886, 2837411, 12560550, 3910107, 6799760, 22389480, 23880299, 12560550

proteinLength

253

geneLength

762

Gene

Coordinates

2,905,571 2,906,332

The protein

Paralogous protein(s)

[[this]]

The protein

[SW|Domains]

[SW|4Fe-4S ferredoxin-type domain] (aa 146-174) (according to UniProt)

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]