SubtiBank SubtiBank
Version comparison:

2017-04-24 15:34:12Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)

proteinLength

333

geneLength

999

Gene

Coordinates

1,662,547 → 1,663,548

Gene

Phenotypes of a mutant

essential [Pubmed|24224907,12682299]

depletion results in sporulation deficiency (via [[protein|SpoIIR]]) [Pubmed|22111992]

a ts mutant forms an abberant Z-ring and has a [SW|cell division] defect [Pubmed|24224907]

essential [Pubmed|24224907,12682299]

depletion results in sporulation deficiency (via [SW|SpoIIR]) [Pubmed|22111992]

a ts mutant forms an abberant Z-ring and has a [SW|cell division] defect [Pubmed|24224907]

The protein

[SW|Localization]

uniformly distributed on the membrane of most cells, but occasionally appears as membrane foci as well [Pubmed|26816052]

in the presence of daptomycin, PlsX delocalizes from the membrane to the cytoplasm [Pubmed|27791134]

localizes to the cell division sites, colocalizes with the Z-ring [Pubmed|24224907]

uniformly distributed on the membrane of most cells, but occasionally appears as membrane foci as well [Pubmed|26816052]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

References

12737802, 19282621, 17645809, 17557823, 8759840, 16932747, 19850612, 16091051, 21383089, 22111992, 24224907, 26816052, 16021622, 27791134

12737802, 19282621, 17645809, 17557823, 8759840, 16932747, 19850612, 16091051, 21383089, 22111992, 24224907, 26816052, 16021622

[SW|Categories] containing this gene/protein

[SW|cell division], [SW|biosynthesis of lipids], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence)

1,662,547 -> 1,663,548

The protein

[SW|Interactions]

[[protein|PlsX]]-[[protein|PlsY]] [Pubmed|19282621]

[[protein|PlsX]]-[[protein|FtsA]] [Pubmed|24224907]

Expression and Regulation

Operon

''[[protein|fapR]]-[[protein|plsX]]-[[protein|fabD]]-[[protein|fabG]]-[[protein|acpA]]'' [Pubmed|12737802,19850612]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|16932747]

Expression and Regulation

Regulation

induced if the cells experience an accumulation of malonyl-CoA ([[protein|FapR]]) [Pubmed|12737802]

expressed at high cell density ([[protein|ComA]]) [Pubmed|16091051]

induced upon fatty acid biosynthesis inhibition [Pubmed|21383089]

Expression and Regulation

Regulatory mechanism

[[protein|ComA]]: transcription activation ([[protein|ComA]]) [Pubmed|16091051]

[[protein|FapR]]: transcription repression [Pubmed|12737802]