SubtiBank SubtiBank
Version comparison:

Sun Jan 17 2016 18:40:51 GMT+0100 (CET)2025-05-13 11:51:03

locus

BSU39260

BSU_39260

outlinks

bsu

BSU39260

BSU_39260

[SW|Categories] containing this gene/protein

[SW|utilization of specific carbon sources]

Gene

Coordinates on the chromosome (coding sequence)

4,032,346 -> 4,033,755

The protein

Catalyzed reaction/ biological activity

6-phospho-beta-D-glucosyl-(1,4)-D-glucose H2O = D-glucose D-glucose 6-phosphate (according to Swiss-Prot)

6-phospho-β-D-glucosyl-(1→4)-D-glucose + H2O --> D-glucose + D-glucose 6-phosphate (according to UniProt)

The protein

Protein family

glycosyl hydrolase 1 family (according to Swiss-Prot)

[SW|glycosyl hydrolase 1 family] (according to UniProt)

The protein

Structure

[PDB|4IPL] (from ''Streptococcus pneumoniae'', 60% identity)

[PDB|4IPL] (from ''Streptococcus pneumoniae'', 60% identity) [Pubmed|23580646]

Expression and Regulation

Operon

''[[protein|bglP]]-[[protein|bglH]]-[[protein|yxiE]]'' [Pubmed|7883710]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|7559347]

Expression and Regulation

Regulation

repressed by glucose ([[protein|CcpA]], [[protein|LicT]]) [Pubmed|7559347]

induced by salicin ([[protein|LicT]]) [Pubmed|7883710]

Expression and Regulation

Regulatory mechanism

[[protein|CcpA]]: transcription repression, ([[protein|CcpA]] binding site overlaps -35 region) [Pubmed|7559347]

[[protein|LicT]]-dependent [SW|RNA switch] (antitermination, lack of [[protein|LicT]]-dependent antitermination in the presence of gucose due to the requirement of [[protein|LicT]] to be phosphorylated by [[PtsH| HPr]] [Pubmed|8626332]

References

14652714, 16672620, 15139916, 7883710, 7559347, 26772920

14652714, 16672620, 15139916, 7883710, 7559347, 26772920, 23580646

proteinLength

469

geneLength

1410

Gene

Coordinates

4,032,346 4,033,755

The protein

Paralogous protein(s)

[[this]]

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

Biological materials

Mutant

BKE39260 ([[gene|bglH]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTGATCACCCCATTAG, downstream forward: _UP4_TGACAATTTTTTGAAAACTC

BKK39260 ([[gene|bglH]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTGATCACCCCATTAG, downstream forward: _UP4_TGACAATTTTTTGAAAACTC