Sun Jan 17 2016 18:40:51 GMT+0100 (CET)2025-05-13 11:51:03
locus
BSU39260
BSU_39260
outlinks
bsu
BSU39260
BSU_39260
[SW|Categories] containing this gene/protein
[SW|utilization of specific carbon sources]
Gene
Coordinates on the chromosome (coding sequence)
4,032,346 -> 4,033,755
The protein
Catalyzed reaction/ biological activity
6-phospho-beta-D-glucosyl-(1,4)-D-glucose H2O = D-glucose D-glucose 6-phosphate (according to Swiss-Prot)
6-phospho-β-D-glucosyl-(1→4)-D-glucose + H2O --> D-glucose + D-glucose 6-phosphate (according to UniProt)
The protein
Protein family
glycosyl hydrolase 1 family (according to Swiss-Prot)
[SW|glycosyl hydrolase 1 family] (according to UniProt)
The protein
Structure
[PDB|4IPL] (from ''Streptococcus pneumoniae'', 60% identity)
[PDB|4IPL] (from ''Streptococcus pneumoniae'', 60% identity) [Pubmed|23580646]
Expression and Regulation
Operon
''[[protein|bglP]]-[[protein|bglH]]-[[protein|yxiE]]'' [Pubmed|7883710]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|7559347]
Expression and Regulation
Regulation
repressed by glucose ([[protein|CcpA]], [[protein|LicT]]) [Pubmed|7559347]
induced by salicin ([[protein|LicT]]) [Pubmed|7883710]
Expression and Regulation
Regulatory mechanism
[[protein|CcpA]]: transcription repression, ([[protein|CcpA]] binding site overlaps -35 region) [Pubmed|7559347]
[[protein|LicT]]-dependent [SW|RNA switch] (antitermination, lack of [[protein|LicT]]-dependent antitermination in the presence of gucose due to the requirement of [[protein|LicT]] to be phosphorylated by [[PtsH| HPr]] [Pubmed|8626332]
References
proteinLength
469
geneLength
1410
Gene
Coordinates
4,032,346 4,033,755
The protein
Paralogous protein(s)
[[this]]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
BKE39260 ([[gene|bglH]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTGATCACCCCATTAG, downstream forward: _UP4_TGACAATTTTTTGAAAACTC
BKK39260 ([[gene|bglH]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATTGATCACCCCATTAG, downstream forward: _UP4_TGACAATTTTTTGAAAACTC