Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)2025-05-27 14:40:01
locus
BSU14850
BSU_14850
ec
outlinks
bsu
BSU14850
BSU_14850
aminos
MLKKMLKSYDYSLIFAIVLLCGFGLVMVYSSSMITAVSRYGVSSNFFFMRQLFALIAGGALFILMALFPYKALAHQKFQKGILLVSVLALISLFVFGHVAGNAQSWFKIGGMSIQPGEFVKLVVILYLAAVYAKKQSYIDHLLTGVAPPVVMTLIICGLIAMQPDFGTAMIIGLIATCMILCSGFSGKTLVRLVILGGIVFILVSPIIYLNQDKILTEGRLARFESLEDPFKYANSSGLQVINSYYAISSGGIFGLGLGESIQKYGYLPESHTDFIMAVIAEELGIFGVLFVIFLLGFVVIKGFYIARKCEDPFGSLLAIGISSMIAIQSFINLGGVSGLIPITGVTLPFISYGGSSLVLLLGSMGILANISMFVKYSENKKKKEPLAPKGMKKKQLKKTVYL
[SW|Categories] containing this gene/protein
[SW|cell division], [SW|essential genes], [SW|membrane proteins]
Gene
Coordinates on the chromosome (coding sequence)
1,552,899 -> 1,554,110
The protein
Catalyzed reaction/ biological activity
principal peptidoglycan glycosyltransferase of the [SW|divisome] [Pubmed|27525505]
principal peptidoglycan glycosyltransferase of the [SW|divisome] [Pubmed|27525505]
[GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphospho-di-trans,octa-cis-undecaprenol + β-D-GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol --> [GlcNAc-(1→4)-Mur2Ac(oyl-L-Ala-γ-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphospho-di-trans-octa-cis-undecaprenol + di-trans,octa-cis-undecaprenyl diphosphate + H+ (according to UniProt)
The protein
Protein family
[SW|FtsW]/[SW|RodA]/[SW|SpoVE] family (according to Swiss-Prot)
[SW|SEDS proteins] (shape, elongation, division, and sporulation) [Pubmed|27525505]
[SW|SEDS proteins] (shape, elongation, division, and sporulation) [Pubmed|27525505]
SEDS family (with [[protein|RodA]] and [[protein|SpoVE]], according to UniProt)
The protein
Paralogous protein(s)
[[protein|RodA]], [SW|SpoVE]
[[this]]
The protein
[SW|Localization]
integral membrane protein
localization depends on [SW|FtsZ] [SW|26679002]
integral membrane protein
localizes to the division site [Pubmed|27895631]
localization depends on [[protein|FtsZ]] [Pubmed|26679002]
The protein
[SW|Interactions]
[[protein|Maf]]-[[protein|FtsW]] [Pubmed|21564336]
may be part of the [SW|divisome] [SW|26679002]
Expression and Regulation
Operon
''[[protein|ftsW]]-[[protein|pycA]]'' (according to [http://dbtbs.hgc.jp/COG/prom/ftsW-pycA.html DBTBS])
Expression and Regulation
Regulation
constitutively expressed [Pubmed|23701187]
Expression and Regulation
Regulatory mechanism
[[protein|YofA]]: transcription activation [Pubmed|17526699]
References
Reviews
References
Original Publications
proteinLength
403
geneLength
1212
Gene
Coordinates
1,552,899 1,554,110
The protein
Structure
[PDB|6BAR] (from Thermus thermophilus,corresponds to aa 97... 359 34% identity) [pubmed|29590088]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-A563 (ftsW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/563 NBRP B. subtilis, Japan]