Tue Dec 13 2016 11:16:35 GMT+0100 (CET)2025-05-14 09:19:24
locus
BSU28550
BSU_28550
ec
outlinks
bsu
BSU28550
BSU_28550
aminos
MKQKRPKYMQIIDAAVEVIAENGYHQSQVSKIAKQAGVADGTIYLYFKNKEDILISLFKEKMGQFIERMEEDIKEKATAKEKLALVISKHFSLLAGDHNLAIVTQLELRQSNLELRQKINEILKGYLNILDGILTEGIQSGEIKEGLDVRLARQMIFGTIDETVTTWVMNDQKYDLVALSNSVLELLVSGIHNK
[SW|Categories] containing this gene/protein
[SW|utilization of lipids], [SW|transcription factors and their control]
Gene
Coordinates on the chromosome (coding sequence)
2,917,957 -> 2,918,541
Expression and Regulation
Operon
''[[protein|lcfA]]-[[protein|fadR]]-[[protein|fadB]]-[[protein|etfB]]-[[protein|etfA]]'' [Pubmed|17189250]
''[[protein|fadR]]-[[protein|fadB]]-[[protein|etfB]]-[[protein|etfA]]'' [Pubmed|17189250]
Expression and Regulation
[SW|Sigma factor]
''[[protein|lcfA]]'': [[protein|SigA]] [Pubmed|21398533]
''[[protein|fadR]]'': [[protein|SigA]] [Pubmed|17189250]
Expression and Regulation
Regulation
induced by long-chain fatty acids ([[protein|FadR]]) [Pubmed|17189250]
subject to carbon catabolite repression ([[protein|CcpA]]-[[PtsH|HPr(Ser-P)]] [Pubmed|21398533]
Expression and Regulation
Regulatory mechanism
[[protein|FadR]]: transcription repression [Pubmed|17189250]
[[protein|CcpA]]-[[PtsH|HPr(Ser-P)]]: transcription repression [Pubmed|21398533]
Biological materials
Mutant
1A853 ( ''fadR''::''cat''), [Pubmed|17085570], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A853&Search=1A853 BGSC]
MGNA-B008 (ysiA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1007 NBRP B. subtilis, Japan]
1A853 ( ''fadR''::''cat''), [Pubmed|17085570], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A853&Search=1A853 BGSC]
BKE28550 ([[gene|fadR]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTTCATCGTTCCTTCC, downstream forward: _UP4_AATAAGTAAAGGAGTTCTGT
BKK28550 ([[gene|fadR]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATGTTCATCGTTCCTTCC, downstream forward: _UP4_AATAAGTAAAGGAGTTCTGT
proteinLength
194
geneLength
585
Gene
Coordinates
2,917,957 2,918,541
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Domains]
[SW|HTH tetR-type domain] (aa 5-65) (according to UniProt)
The protein
Structure
[PDB|3WHB] [pubmed|24356978]
The protein
additional information
information on binding sites can be found in the [http://www.prodoric2.de/detail.php?acc=MX000195 PRODORIC2 database]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]