SubtiBank SubtiBank
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2020-01-16 10:02:402025-05-22 12:37:09

function

cell division or sugar metabolism

cell division

The protein

Catalyzed reaction/ biological activity

Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains (according to UniProt)

Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains (according to UniProt)

cleavage of [[protein|MgtE]] between its first and second trans-membrane helix at low magnesium concentration or high manganese or zinc concentrations to prevent uptake of toxic metal ions [pubmed|31930742]

acts as adapter protein for [[protein|FtsH]] [pubmed|31930742]

References

Original publications

15050034, 22921757, 15616571

15050034, 22921757, 15616571, 31930742

The protein

Effectors of protein activity

Mn2+ and Zn2+ bind to the N-terminal cytosolic domain of YqgE to stimulate [[protein|MgtE]] degradation [pubmed|31930742]