2017-8-11 16:0:3Thu Oct 13 2016 18:19:35 GMT+0200 (CEST)
description
negative regulator of scoC expression, activator of PtkA kinase activity
negative regulator of scoC expression
proteinLength
352
geneLength
1056
Gene
Coordinates
157,421 → 158,479
Gene
Phenotypes of a mutant
increased expression of ''[[gene|aprE]]'' (due to loss of repression of ''[[gene|scoC]]'' expression)
increased expression of ''[[protein|aprE]]'' (due to loss of repression of ''[[protein|scoC]]'' expression)
The protein
Catalyzed reaction/ biological activity
transcription repression of ''[[gene|scoC]]'' expression [SW|26094643]
transcription repression of ''[[protein|scoC]]'' expression [SW|26094643]
The protein
[SW|Domains]
DNA-binding domain: aa 1 - 60 [Pubmed|26094643]
ATP-binding Walker domain: aa 105 - 275 [Pubmed|26094643]
domain for the interaction with [[protein|PtkA]]: aa 294 - 352
DNA-binding domain: aa 1 - 60 [Pubmed|26094643]
ATP-binding Walker domain: aa 105 - 275 [Pubmed|26094643]
domain for the interaction with [SW|PtkA]: aa 294 - 352
The protein
Modification
[[protein|PtkA]]-dependent phosphorylation at Tyr-327 results in better binding of the target promoter [Pubmed|26094643]
[SW|PtkA]-dependent phosphorylation at Tyr-327 results in better binding of the target promoter [Pubmed|26094643]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
References
[SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|transition state regulators]
Gene
Coordinates on the chromosome (coding sequence)
157,421 -> 158,479
The protein
[SW|Interactions]
[SW|SalA]-[SW|PtkA], for phosphorylation of [SW|SalA] [Pubmed|26094643]
Expression and Regulation
Regulation
negative autoregulation