Tue Dec 13 2016 11:16:31 GMT+0100 (CET)2025-05-29 08:47:42
locus
BSU11670
BSU_11670
outlinks
bsu
BSU11670
BSU_11670
aminos
MKRHYEAVVIGGGIIGSAIAYYLAKENKNTALFESGTMGGRTTSAAAGMLGAHAECEERDAFFDFAMHSQRLYKGLGEELYALSGVDIRQHNGGMFKLAFSEEDVLQLRQMDDLDSVSWYSKEEVLEKEPYASGDIFGASFIQDDVHVEPYFVCKAYVKAAKMLGAEIFEHTPVLHVERDGEALFIKTPSGDVWANHVVVASGVWSGMFFKQLGLNNAFLPVKGECLSVWNDDIPLTKTLYHDHCYIVPRKSGRLVVGATMKPGDWSETPDLGGLESVMKKAKTMLPAIQNMKVDRFWAGLRPGTKDGKPYIGRHPEDSRILFAAGHFRNGILLAPATGALISDLIMNKEVNQDWLHAFRIDRKEAVQI
[SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors]
Gene
Coordinates on the chromosome (coding sequence)
1,243,735 -> 1,244,844
The protein
Catalyzed reaction/ biological activity
Glycine + H2O + O2 = glyoxylate + NH3 + H2O2 (according to Swiss-Prot)
glycine + H2O + O2 --> glyoxylate + H2O2 + NH4+ (according to UniProt)
H2O + N-ethylglycine + O2 --> ethylamine + glyoxylate + H2O2 (according to UniProt)
H2O + O2 + sarcosine --> glyoxylate + H2O2 + methylamine (according to UniProt)
D-alanine + H2O + O2 --> H2O2 + NH4+ + pyruvate (according to UniProt)
glyphosate + H2O + O2 --> aminomethylphosphonate + glyoxylate + H+ + H2O2 (according to UniProt)
The protein
Protein family
DAMOX/DASOX family (according to Swiss-Prot)
DAO family (single member, according to UniProt)
The protein
[SW|Interactions]
the FAD-containing holoenzyme is a homotetramer [Pubmed|19751796]
Expression and Regulation
Operon
''[[protein|tenA]]-[[protein|tenI]]-[[protein|thiO]]-[[protein|thiS]]-[[protein|thiG]]-[[protein|thiF]]-[[protein|thiD]]'' [Pubmed|1898926]
Expression and Regulation
Regulation
repressed by thiamine ([[protein|Thi-box]]) [Pubmed|16356850]
Expression and Regulation
Regulatory mechanism
[[protein|Thi-box]]: [SW|RNA switch] [Pubmed|16356850]
References
Original publications
proteinLength
369
geneLength
1110
Gene
Coordinates
1,243,735 1,244,844
The protein
Paralogous protein(s)
[[this]]
The protein
[SW|Cofactors]
FAD (according to UniProt)
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B164 (yjbR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1163 NBRP B. subtilis, Japan]
BKE11670 ([[gene|thiO]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AATTCCGCCTCCAATCACCA, downstream forward: _UP4_CGCAAGGAGGCGGTTCAGAT
BKK11670 ([[gene|thiO]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11670 BGSC], [Pubmed|28189581], upstream reverse: _UP1_AATTCCGCCTCCAATCACCA, downstream forward: _UP4_CGCAAGGAGGCGGTTCAGAT