Tue May 31 2016 20:05:01 GMT+0200 (CEST)2025-05-30 01:14:30
product
cortex morphogenic protein A, adapter protein targeting SpoIVA for degradation by ClpXP upon spore envelope defects
cortex morphogenic protein A, adapter protein targeting [[protein|SpoIVA]] for degradation by [[protein|ClpXP]] upon spore envelope defects
essential
ec
[SW|Categories] containing this gene/protein
[SW|sporulation proteins]
Gene
Coordinates on the chromosome (coding sequence)
525,021 -> 528,076
Gene
Phenotypes of a mutant
quicker progressing through the [SW|sporulation ] cycle [Pubmed|22463703]
overexpression of CmpA results in heat-sensitive sporulation [Pubmed|22463703,26387458], this can be suppressed by mutations in ''[SW|clpP]'' and ''[SW|clpX]'' [Pubmed|26387458]
quicker progressing through the [SW|sporulation ] cycle [Pubmed|22463703]
overexpression of CmpA results in heat-sensitive sporulation [Pubmed|22463703,26387458], this can be suppressed by mutations in ''[[gene|clpP]]'' and ''[[gene|clpX]]'' [Pubmed|26387458]
Protein
Catalyzed reaction/ biological activity
orchestrates spore coat and cortex assembly [Pubmed|22463703]
represses cortex assembly until spore coat assembly successfully initiates [Pubmed|22463703]
Protein
[SW|Localization]
surface of the developing spore, this depends on a functional [SW|SpoIVA] [Pubmed|22463703,26387458]
Protein
[SW|Interactions]
[SW|ClpX]-[SW|CmpA] (for [SW|ClpX]-[SW|ClpP]-dependent degradation of [SW|SpoIVA]) [Pubmed|26387458]
[SW|CmpA]-[SW|SpoIVA] (for [SW|ClpX]-[SW|ClpP]-dependent degradation of [SW|SpoIVA]) [Pubmed|26387458]
Expression and Regulation
Operon
''[SW|cmpA] '' [Pubmed|22463703,20709900]
Expression and Regulation
Sigma factor
[SW|SigE] [Pubmed|22463703]
Expression and Regulation
Regulation
expressed in mother cell during [SW|sporulation ] ([[protein|SigE]], [SW|SpoIIID]) [Pubmed|22463703]
Expression and Regulation
Regulatory mechanism
[SW|SpoIIID]: transcription activation [Pubmed|22463703]
References
Reviews
Gene
Coordinates
525,021 → 528,076
The protein
Catalyzed reaction/ biological activity
orchestrates spore coat and cortex assembly [Pubmed|22463703]
represses cortex assembly until spore coat assembly successfully initiates [Pubmed|22463703]
The protein
[SW|Localization]
surface of the developing spore, this depends on a functional [[protein|SpoIVA]] [Pubmed|22463703,26387458]
The protein
[SW|Interactions]
[[protein|ClpX]]-[[protein|CmpA]] (for [[protein|ClpX]]-[[protein|ClpP]]-dependent degradation of [[protein|SpoIVA]]) [Pubmed|26387458]
[[protein|CmpA]]-[[protein|SpoIVA]] (for [[protein|ClpX]]-[[protein|ClpP]]-dependent degradation of [[protein|SpoIVA]]) [Pubmed|26387458]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]