2017-04-10 10:42:59Thu Jan 12 2017 11:44:06 GMT+0100 (CET)
proteinLength
378
geneLength
1134
product
DNA polymerase III (beta subunit), beta clamp
DNA polymerase III
(beta subunit), beta clamp
Gene
Coordinates
1,939 -> 3,075
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
References
Reviews
[SW|Categories] containing this gene/protein
[SW|DNA replication], [SW|DNA repair/ recombination], [SW|essential genes]
Gene
Coordinates on the chromosome (coding sequence)
1,939 -> 3,075
The protein
[SW|Interactions]
[[protein|DnaA]]-[[protein|YabA]]-[[protein|DnaN]] [Pubmed|12060778]
part of the [SW|replisome]: [[protein|PolC]]-[[protein|HolA]]-[[protein|HolB]]-[[protein|DnaX]]-[[protein|DnaN]]-[[protein|DnaG]]-[[protein|DnaC]]-[[protein|DnaI]]-[[protein|DnaD]]-[[protein|SsbA]]-[[protein|DnaE]]-[[protein|PriA]]-[[protein|DnaB]] [Pubmed|20122408]
[SW|PolY1]-[[protein|DnaN]], [SW|PolY2]-[[protein|DnaN]] (required for untargeted mutagenesis) [Pubmed|15469515]
[SW|PolY1]-[[protein|PolA]]-[[protein|DnaN]] [Pubmed|16045613]
[[protein|MutL]] (C-terminal domain)-[[protein|DnaN]], the interaction stimulates the endonuclease activity of [SW|MutL] [Pubmed|26384423,21050827]
[[protein|MutS]]-[[protein|DnaN]] [Pubmed|20453097]
[[protein|DnaE]]-[[protein|DnaN]] [Pubmed|21958350]
[[protein|DnaN]] forms dimers [Pubmed|16045613]
Expression and Regulation
Operon
''[[protein|dnaA]]-[[protein|dnaN]]'' [Pubmed|2987848]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|2987848]
Expression and Regulation
Regulation
negatively controlled by [[protein|DnaA]] [Pubmed|2168872] and [SW|Spo0A] [Pubmed|14651647]
repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
Expression and Regulation
Regulatory mechanism
[SW|Spo0A]: transcription repression [Pubmed|14651647]