SubtiBank SubtiBank
Version comparison:

2017-04-10 10:42:59Thu Jan 12 2017 11:44:06 GMT+0100 (CET)

proteinLength

378

geneLength

1134

product

DNA polymerase III (beta subunit), beta clamp

DNA polymerase III
(beta subunit), beta clamp

Gene

Coordinates

1,939 -> 3,075

Expression and Regulation

Operons

[[this]]

Expression and Regulation

Other regulations

[[this]]

References

Reviews

20157337, 22933559, 26343983, 28075389

20157337, 22933559, 26343983

[SW|Categories] containing this gene/protein

[SW|DNA replication], [SW|DNA repair/ recombination], [SW|essential genes]

Gene

Coordinates on the chromosome (coding sequence)

1,939 -> 3,075

The protein

[SW|Interactions]

[[protein|DnaA]]-[[protein|YabA]]-[[protein|DnaN]] [Pubmed|12060778]

part of the [SW|replisome]: [[protein|PolC]]-[[protein|HolA]]-[[protein|HolB]]-[[protein|DnaX]]-[[protein|DnaN]]-[[protein|DnaG]]-[[protein|DnaC]]-[[protein|DnaI]]-[[protein|DnaD]]-[[protein|SsbA]]-[[protein|DnaE]]-[[protein|PriA]]-[[protein|DnaB]] [Pubmed|20122408]

[SW|PolY1]-[[protein|DnaN]], [SW|PolY2]-[[protein|DnaN]] (required for untargeted mutagenesis) [Pubmed|15469515]

[SW|PolY1]-[[protein|PolA]]-[[protein|DnaN]] [Pubmed|16045613]

[[protein|MutL]] (C-terminal domain)-[[protein|DnaN]], the interaction stimulates the endonuclease activity of [SW|MutL] [Pubmed|26384423,21050827]

[[protein|MutS]]-[[protein|DnaN]] [Pubmed|20453097]

[[protein|DnaE]]-[[protein|DnaN]] [Pubmed|21958350]

[[protein|DnaN]] forms dimers [Pubmed|16045613]

Expression and Regulation

Operon

''[[protein|dnaA]]-[[protein|dnaN]]'' [Pubmed|2987848]

Expression and Regulation

[SW|Sigma factor]

[[protein|SigA]] [Pubmed|2987848]

Expression and Regulation

Regulation

negatively controlled by [[protein|DnaA]] [Pubmed|2168872] and [SW|Spo0A] [Pubmed|14651647]

repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]

Expression and Regulation

Regulatory mechanism

[SW|Spo0A]: transcription repression [Pubmed|14651647]