SubtiBank SubtiBank
Version comparison:

2018-11-07 17:15:272025-05-28 04:13:41

locus

BSU00020

BSU_00020

geneLength

1134

1137

outlinks

bsu

BSU00020

BSU_00020

Gene

Coordinates

1,939 → 3,075

1,939 3,075

The protein

Catalyzed reaction/ biological activity

[[protein|DnaN]] overexpression or release from the [SW|replisome] decreases association of [[protein|YabA]] with ''oriC'', increases association of [[protein|DnaA]] with ''oriC'' [Pubmed|21895792]

Deoxynucleoside triphosphate DNA(n) = diphosphate DNA(n 1) (according to Swiss-Prot)

recruits [[protein|MutS]] to the site of [SW|DNA replication] ([SW|replisome]) [Pubmed|23228104]

required for bacteriophage SPP1 replication [Pubmed|23268446]

inhibits oligomerization and helix formation of [[protein|DnaA]] [Pubmed|23909787]

[[protein|DnaN]] overexpression or release from the [SW|replisome] decreases association of [[protein|YabA]] with ''oriC'', increases association of [[protein|DnaA]] with ''oriC'' [Pubmed|21895792]

recruits [[protein|MutS]] to the site of [SW|DNA replication] ([SW|replisome]) [Pubmed|23228104]

required for bacteriophage SPP1 replication [Pubmed|23268446]

inhibits oligomerization and helix formation of [[protein|DnaA]] [Pubmed|23909787]

The protein

Structure

[PDB|4TR6] [pubmed|25170813]

[PDB|4TR6] [pubmed|25170813]

[PDB|6E8D] (complex with [[protein|MutL]]) [Pubmed|30916336]

labs

[SW|Philippe Noirot], Jouy-en-Josas, France [http://locus.jouy.inra.fr/cms/index.php?id=18 homepage]

References

Original publications

16942601, 9822387, 14651647, 2987848, 2168872, 14651647, 12060778, 16461910, 16479537, 19737352, 19081080, 11395445, 20122408, 20451384, 15469515, 16045613, 21895792, 20453097, 23228104, 23268446, 21050827, 21419346, 21958350, 23909787, 25170813, 26384423, 26615189, 27369079, 28878042, 25170813

16942601, 9822387, 14651647, 2987848, 2168872, 14651647, 12060778, 16461910, 16479537, 19737352, 19081080, 11395445, 20122408, 20451384, 15469515, 16045613, 21895792, 20453097, 23228104, 23268446, 21050827, 21419346, 21958350, 23909787, 25170813, 26384423, 26615189, 27369079, 28878042, 25170813, 30391220, 30916336

The protein

Protein family

Beta sliding clamp family (single member, according to UniProt)

Labs working on this gene/protein

[SW|Philippe Noirot], Jouy-en-Josas, France [http://locus.jouy.inra.fr/cms/index.php?id=18 homepage]