Tue Dec 13 2016 11:16:37 GMT+0100 (CET)2025-05-13 08:39:34
description
unknown, the yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ operon may be implicated in the utilization of a modified cysteine variant
cis-aconitate decarboxylase
locus
BSU39460
BSU_39460
function
unknown
metabolite conversion
product
unknown
cis-aconitate decarboxylase
ec
outlinks
bsu
BSU39460
BSU_39460
aminos
MSKQGLTAGLAEAVRTSQPEHSVDAIHEAKKGLLDFTAASFAGREDKGIQKLLRLIEDEGGRPLVPVIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPSAVIVPALIASAARGHDERLLGAYVVGVEVMARLGESIGSRHYEKGWHNTGTLGAIAAACAVGYAEELTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFGGSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAVRQLISEETISAANTERIEVIFPPGGDAALTERSPKAGEEGRFSVEYVIALALHGHGLTVEHFSSQPIPNGVQTTMGRIQRVYDNAIQPAPHAVPKGRFTIVRAYLSDGRICEARVDCPKGAPGNELSEEDIIEKLTLTVPQEKARRIITAVEKADIKEFLAHIE
[SW|Categories] containing this gene/protein
[SW|proteins of unknown function]
Gene
Coordinates on the chromosome (coding sequence)
4,055,536 -> 4,056,873
The protein
Protein family
prpD family (according to Swiss-Prot)
prpD family (with [[protein|MmgE]], according to UniProt)
Expression and Regulation
Operon
''[[protein|yxeK]]-[[protein|snaB]]-[[protein|yxeM]]-[[protein|yxeN]]-[[protein|yxeO]]-[[protein|sndB]]-[[protein|yxeQ]]'' [Pubmed|10746760]
Expression and Regulation
[SW|Sigma factor]
[[protein|SigA]] [Pubmed|16513748]
Expression and Regulation
Regulation
repressed in the presence of cysteine ([[protein|CymR]]) [Pubmed|16513748]
Expression and Regulation
Regulatory mechanism
[[protein|CymR]]: transcription repression [Pubmed|16513748]
References
proteinLength
445
geneLength
1338
Gene
Coordinates
4,055,536 4,056,873
The protein
Catalyzed reaction/ biological activity
cis-aconitate --> itaconate + CO2 [pubmed|32647315]
The protein
Paralogous protein(s)
[[this]]
The protein
Structure
[PDB|7BRA] [pubmed|32647315]
Expression and Regulation
Operons
[[this]]
Expression and Regulation
Other regulations
[[this]]
Biological materials
Mutant
MGNA-B713 (yxeQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1712 NBRP B. subtilis, Japan]
BKE39460 ([[gene|yxeQ]]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE39460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ACCTGCTGTCAGCCCTTGTT, downstream forward: _UP4_TAAGATCAACTCTATTCGGT
BKK39460 ([[gene|yxeQ]]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK39460 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ACCTGCTGTCAGCCCTTGTT, downstream forward: _UP4_TAAGATCAACTCTATTCGGT